P0DXD5 · STSC_STRE0
- ProteinSomaliensene A/B synthase
- GenestsC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids299 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Sesterterpene cyclase, which converts geranylfarnesyl diphosphate (GFPP) into the terpenes somaliensene A and somaliensene B.
Catalytic activity
- (2E,6E,10E,14E)-geranylfarnesyl diphosphate = diphosphate + somaliensene AThis reaction proceeds in the forward direction.
Cofactor
Pathway
Secondary metabolite biosynthesis; terpenoid biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | lyase activity |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSomaliensene A/B synthase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Kitasatosporales > Streptomycetaceae > Streptomyces
Accessions
- Primary accessionP0DXD5
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 32-49 | Helical | ||||
Sequence: WTTLFPATCFVLAAAVHT | ||||||
Transmembrane | 56-72 | Helical | ||||
Sequence: TAVAVASGVLYFWLFVY | ||||||
Transmembrane | 110-132 | Helical | ||||
Sequence: IAVRVAFPLYGWFLGVLEWALLW | ||||||
Transmembrane | 153-171 | Helical | ||||
Sequence: LYAGIGVVAQLAAAWEIVA | ||||||
Transmembrane | 177-194 | Helical | ||||
Sequence: AWRWIVTLTITVTLLMSV | ||||||
Transmembrane | 222-241 | Helical | ||||
Sequence: VFLCAGFALGPLAIHHFLMA | ||||||
Transmembrane | 247-269 | Helical | ||||
Sequence: WWIVATDVVLGGLSLLLAFRVVL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000460726 | 1-299 | Somaliensene A/B synthase | |||
Sequence: MTTMTTNTRRTVWRTVWREIHVSWLFIRSDRWTTLFPATCFVLAAAVHTRLPPAETAVAVASGVLYFWLFVYEHTLANQLVGLEEDRVNKPLRPLVSGRSSVRGARLRLIAVRVAFPLYGWFLGVLEWALLWQVLSLLQHEGGWGRHWLGRNLYAGIGVVAQLAAAWEIVAPVTPDAWRWIVTLTITVTLLMSVQDLRDITGDRAVGRSTMPLVFGERNTRVFLCAGFALGPLAIHHFLMAPAGPHWWIVATDVVLGGLSLLLAFRVVLRRGQRSDQHTYRLVEQWYTLALAASLYTLR |
Structure
Sequence
- Sequence statusComplete
- Length299
- Mass (Da)33,833
- Last updated2024-07-24 v1
- Checksum2A6A23F2F23FA3C2