P0DTL8 · ORF4_HEVPA
- ProteinProtein ORF4
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids158 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Acts by interacting with multiple viral and host proteins to enhance the activity of viral RNA-dependent RNA polymerase.
Miscellaneous
This ORF is only found in HEV genotype 1.
Names & Taxonomy
Protein names
- Recommended nameProtein ORF4
Organism names
- Strain
- Taxonomic lineage
- Virus hosts
Accessions
- Primary accessionP0DTL8
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000456945 | 1-158 | Protein ORF4 | |||
Sequence: MLRGQQIWLSNLTQPQTSAGPVPAVESPPALCSTSLPQVCLDPASPALLPKPTWTLSWSRPGSCVMPGAAAASLLSPRTLRLESPRGAGLSLMRPRPFPLICCCSTCSGPPPSTFLATRIRSQPSILSTPGSFPPSGPIWPPPPGGMLPIAALRMYVS |
Expression
Induction
Endoplasmic reticulum stress conditions initiate the internal translation of ORF4 driven by an internal ribosome entry site-like (IRESl) element.
Structure
Family & Domains
Family and domain databases
Sequence
- Sequence statusComplete
- Length158
- Mass (Da)16,521
- Last updated2022-12-14 v1
- Checksum236918A7D4E1C511