P0DKB8 · LPXC3_ARATH
- ProteinProbable UDP-3-O-acyl-N-acetylglucosamine deacetylase 3, mitochondrial
- GeneLPXC3
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids326 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that in bacteria anchors the lipopolysaccharide to the outer membrane of the cell. Lipid A-like molecules in plants may serve as structural components of the outer membranes of mitochondria and/or chloroplasts, or may be involved in signal transduction or plant defense responses (Potential).
Miscellaneous
Plants silencing LPXC do not have altered morphology compared to wild-type plants when grown under normal growth conditions, but they do not accumulate 2,3-diacylglucosamine-1-phosphate.
Catalytic activity
- a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate
Cofactor
Pathway
Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Molecular Function | metal ion binding | |
Molecular Function | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity | |
Molecular Function | UDP-3-O-acyl-N-acetylglucosamine deacetylase activity | |
Biological Process | lipid A biosynthetic process | |
Biological Process | lipid X metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProbable UDP-3-O-acyl-N-acetylglucosamine deacetylase 3, mitochondrial
- EC number
- Short namesUDP-3-O-acyl-GlcNAc deacetylase 3
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionP0DKB8
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transit peptide | 1-21 | Mitochondrion | ||||
Sequence: MRLPVTVKATKPSFLVIWIRY | ||||||
Chain | PRO_0000419659 | 22-326 | Probable UDP-3-O-acyl-N-acetylglucosamine deacetylase 3, mitochondrial | |||
Sequence: SSAASSPTVSLNPSGRLQQTLAGSVEVKGKSLHSGKFSTVKLNPEIAGAGRFFEFRSRFIPASIEFAQESPLCTTLLKDELKIRTVEHLLSALEAKGVDNCRIQIESESSDDREVEVPIFDGSAKEWVDAIQGVGINAAQNHDGESVEKMVAHVNKPVYVCKNDTFVAAFPALETRITCGIDFPQVPAIGCQWFSWRPIHESSFAKDIASSRTFCVYEEVERMREAGLIKGGSLDNAIVCSAEHGWMNPPLRFDDEACRHKILDLIGDLSLVSRGGNGGLPVAHIVAYKAGHALHTDLARHLTMD |
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.
P0DKB8-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length326
- Mass (Da)35,717
- Last updated2012-10-03 v1
- ChecksumCBF391A5DFB4EEA9
Sequence caution
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC004133 EMBL· GenBank· DDBJ | AAG03128.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002684 EMBL· GenBank· DDBJ | AEE30573.2 EMBL· GenBank· DDBJ | Genomic DNA | ||
AK118128 EMBL· GenBank· DDBJ | BAC42754.1 EMBL· GenBank· DDBJ | mRNA |