P0CZ66 · HUTG_STRP3

Function

function

Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 manganese ions per subunit.

Pathway

Amino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (hydrolase route): step 1/1.

Features

Showing features for binding site.

132850100150200250300
TypeIDPosition(s)Description
Binding site133Mn2+ 1 (UniProtKB | ChEBI)
Binding site159Mn2+ 1 (UniProtKB | ChEBI)
Binding site159Mn2+ 2 (UniProtKB | ChEBI)
Binding site161Mn2+ 2 (UniProtKB | ChEBI)
Binding site163Mn2+ 1 (UniProtKB | ChEBI)
Binding site253Mn2+ 1 (UniProtKB | ChEBI)
Binding site253Mn2+ 2 (UniProtKB | ChEBI)
Binding site255Mn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionagmatinase activity
Molecular Functionformimidoylglutamase activity
Molecular Functionmanganese ion binding
Biological ProcessL-histidine catabolic process to glutamate and formamide
Biological ProcessL-histidine catabolic process to glutamate and formate
Biological Processputrescine biosynthetic process from arginine, using agmatinase

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Formimidoylglutamase
  • EC number
  • Alternative names
    • Formiminoglutamase
    • Formiminoglutamate hydrolase

Gene names

    • Name
      hutG
    • Ordered locus names
      SpyM3_1780

Organism names

Accessions

  • Primary accession
    P0CZ66
  • Secondary accessions
    • Q8K5L4

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001737761-328Formimidoylglutamase

Structure

Family & Domains

Sequence similarities

Belongs to the arginase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    328
  • Mass (Da)
    36,373
  • Last updated
    2011-07-27 v1
  • Checksum
    23C6FBFA18FC748B
MLEDYYPSTTSYYHSGIDDDLYTAKWGMVMTFLDLNDSSLTPFEGTHFALIGFKSDKGVYINNGRVGAVESPAAIRTQLAKFPWHLGNQVMVYDVGNIDGPNRSLEQLQNSLSKAIKRMCDLNLKPIVLGGGHETAYGHYLGLRQSLSSSDDLAVINMDAHFDLRPYDQTGPNSGTGFRQMFDDAVADKRLFKYFVLGIQEHNNNLFLFDFVAKSKGIQFLTGQDIYQMGHQKVCRAIDRFLEGQERVYLTIDMDCFSVGAAPGVSAIQSLGVDPNLAVLVLQHIAASGKLVGFDVVEVSPPHDIDNHTANLAATFIFYLVQIMAQHN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE014074
EMBL· GenBank· DDBJ
AAM80387.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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