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P0CR64 · SNX41_CRYNJ

Function

function

May be required for cytoplasm to vacuole transport (Cvt) and pexophagy.

Features

Showing features for binding site.

163850100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site118a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) (UniProtKB | ChEBI)
Binding site120a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) (UniProtKB | ChEBI)
Binding site144a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) (UniProtKB | ChEBI)
Binding site168a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentendosome membrane
Molecular Functionphosphatidylinositol binding
Biological Processautophagy
Biological Processprotein transport
Biological Processretrograde transport, endosome to Golgi

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Sorting nexin-41

Gene names

    • Name
      SNX41
    • Ordered locus names
      CNC03560

Organism names

Accessions

  • Primary accession
    P0CR64
  • Secondary accessions
    • Q55VX2
    • Q5KKB9

Proteomes

Subcellular Location

Endosome membrane
; Peripheral membrane protein
Endomembrane system
; Peripheral membrane protein
Note: Endosome and other perivacuolar punctate structures.

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002138271-638Sorting nexin-41

Proteomic databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-69Disordered
Compositional bias11-32Pro residues
Domain84-201PX
Region215-239Disordered
Compositional bias217-239Polar residues
Region408-432Disordered
Region545-638Disordered
Compositional bias548-574Polar residues
Compositional bias576-598Basic and acidic residues

Domain

The PX domain binds phosphatidylinositol 3-phosphate which is necessary for peripheral membrane localization to the perivacuolar punctate structures.

Sequence similarities

Belongs to the sorting nexin family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    638
  • Mass (Da)
    70,714
  • Last updated
    2011-06-28 v1
  • MD5 Checksum
    5F17C01875D5A3445BDA9AA43144C189
MDSDTSPNPFASSPPSSPSPRPSLPPPVPRKPSSLVSAASGSPPPTHRASFPDPARHPKMGATVPGPKPKTGYCCSIDKDISAGEQVHIVDALKTTEGGTASYITYVIRLGTHTVRRRYSAFLSLHQSLTGLYPVLIIPPIPSKQSLTDYAVKGQSKAREDATIIARRKRLLEDFLQRLIRHPILGGEHVLHRFLEEDVSWSEVLHSPPISLLSKNPLHAPSHNPTFQPTTPTSPSEAPATTSYIAHHLLPTPSPSHPLRQPDQRFMDSEAFTEKFQSHFSGTMEKVNRRVTKRWGERAHDMSELGGIWNGFSLVEQGKLGDAIEKVGRAVDAEYLATAALLQSWEKTTTEPLHIYSQFATLIRARLSFRHQKHVQYELVQEALETQRDKLEILENAEREARRLEEALERGGSVLASPQLEPEAARDERERAQRRARASQGFGLLSAVKHSLSGMIDMDPEATRRANIAKTRDNISQLEDSYQAAAQDLKYASMTLQADLDRFQRQKVADLREMAINLSQVHRDWCKQNLEAWKAAQAAVREIDPHPNRPAQTQTQVQSQQSHAGPSTLHAQTEDDVSKLGVDAMKNEIERVEIEIADKPLPKPSLAETGGDGVVPSPQPRQENDTEEQEGHGPLGPL

Sequence caution

The sequence AAW42383.2 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias11-32Pro residues
Compositional bias217-239Polar residues
Compositional bias548-574Polar residues
Compositional bias576-598Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE017343
EMBL· GenBank· DDBJ
AAW42383.2
EMBL· GenBank· DDBJ
Genomic DNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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