P0CP66 · CPK1_CRYNJ

Function

function

Responds to activation by environmental stress by phosphorylating downstream targets.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Activity regulation

Activated by tyrosine and threonine phosphorylation.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site22-30ATP (UniProtKB | ChEBI)
Binding site45ATP (UniProtKB | ChEBI)
Active site140Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular FunctionMAP kinase activity
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processintracellular signal transduction
Biological Processprotein phosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mitogen-activated protein kinase CPK1
  • EC number
  • Alternative names
    • Stress-activated protein kinase CPK1

Gene names

    • Name
      CPK1
    • Ordered locus names
      CNE00520

Organism names

Accessions

  • Primary accession
    P0CP66
  • Secondary accessions
    • Q55SZ2
    • Q5KHC4
    • Q8NK05

Proteomes

Organism-specific databases

Subcellular Location

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00001863241-366Mitogen-activated protein kinase CPK1
Modified residue181Phosphothreonine
Modified residue183Phosphotyrosine

Post-translational modification

Dually phosphorylated on Thr-181 and Tyr-183, which activates the enzyme.

Keywords

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, motif.

TypeIDPosition(s)Description
Domain17-302Protein kinase
Motif181-183TXY

Domain

The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    366
  • Mass (Da)
    42,120
  • Last updated
    2011-06-28 v1
  • Checksum
    1BA353D5D67CF84E
MTIDQSQINFNVPSTYKLEEIVGEGAYGLVVAGTHLPSGTQVAIKRITPFDHTMFCQRTLREIKLLRHFHHENIISILDLIQPESYEVFNEVYLVQELMETDLHRVIRSQELSDDHCQYFVYQTLRGLKALHSADVLHRDLKPSNLLLNANCDLKICDFGLARSSAKPPPGTSDGGQGFMTEYVATRWYRAPEVMLSFQEYTKAIDLWSVGCILAEMINGKPLFPGRDYHHQLSLILQVLGTPTMDDFNEITSQRSKDYLRALEFTRRQDFSAICPKAKPAAVDLLKQTLTFSPSKRITVEEALMHSYVEAYHDPHDEPNAEPLKPGFFDFEFHQEKLSRDQWKRMIYDEVQDPVPTILSQWTESH

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF414186
EMBL· GenBank· DDBJ
AAN03694.1
EMBL· GenBank· DDBJ
Genomic DNA
AE017345
EMBL· GenBank· DDBJ
AAW43453.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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