P0CP45 · EFM7_CRYNB
- ProteinProtein N-terminal and lysine N-methyltransferase EFM7
- GeneEFM7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids299 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 74 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: W | ||||||
Binding site | 100-102 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: GAG | ||||||
Binding site | 122 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 155 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: W | ||||||
Binding site | 178 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: S |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | N-terminal protein N-methyltransferase activity | |
Molecular Function | protein-lysine N-methyltransferase activity | |
Biological Process | N-terminal peptidyl-glycine methylation | |
Biological Process | peptidyl-lysine dimethylation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameProtein N-terminal and lysine N-methyltransferase EFM7
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Tremellomycetes > Tremellales > Cryptococcaceae > Cryptococcus > Cryptococcus neoformans species complex
Accessions
- Primary accessionP0CP45
- Secondary accessions
Organism-specific databases
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000410180 | 1-299 | Protein N-terminal and lysine N-methyltransferase EFM7 | |||
Sequence: MSQDPILTSKGSQEEEDFFGLDNFFPEPESPLPPPFSFASYDIPANIDFYVPDHRKSLILRLVGSHPLWGHHLWNTARTLSTYLLETPQITQSRHVLELGAGAGLPSIVCVLAGSSKVIVTDYSDEGLLDNLRFNVDVNLEGEEKERIAVDGHVWGQSVDPLLGHLPKGQKYDLLILSDLVFNHSQHDALIKTVEATLTSSSTQSYDPSNPSAPLTEPSILVFFTHHRPHLAHADMAFFPRLAESGNGWAYEKVVEEWAGAMFENDPGDKKVRGTVHGWRAWRVRDGEERGEKPSRISL |
Structure
Sequence
- Sequence statusComplete
- Length299
- Mass (Da)33,358
- Last updated2011-06-28 v1
- Checksum6727D5648AF256EA
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AAEY01000038 EMBL· GenBank· DDBJ | EAL19580.1 EMBL· GenBank· DDBJ | Genomic DNA |