P0C957 · PLB1_ASPFU

Function

function

Catalyzes the release of fatty acids from lysophospholipids.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentendoplasmic reticulum
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular Functionlysophospholipase activity
Molecular Functionphospholipase A2 activity
Biological Processglycerophospholipid catabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Lysophospholipase 1
  • EC number
  • Alternative names
    • Phospholipase B 1

Gene names

    • Name
      plb1
    • ORF names
      AFUA_4G08720

Organism names

Accessions

  • Primary accession
    P0C957
  • Secondary accessions
    • Q4WPC0
    • Q6U820
    • Q9P8P5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Phenotypes & Variants

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant498in strain: ATCC 90240 / AF-10
Natural variant590-593in strain: ATCC 90240 / AF-10

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 2 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

Protein family/group databases

PTM/Processing

Features

Showing features for signal, chain, glycosylation, lipidation, propeptide.

TypeIDPosition(s)Description
Signal1-20
ChainPRO_000024555521-609Lysophospholipase 1
Glycosylation64N-linked (GlcNAc...) asparagine
Glycosylation104N-linked (GlcNAc...) asparagine
Glycosylation139N-linked (GlcNAc...) asparagine
Glycosylation173N-linked (GlcNAc...) asparagine
Glycosylation246N-linked (GlcNAc...) asparagine
Glycosylation290N-linked (GlcNAc...) asparagine
Glycosylation329N-linked (GlcNAc...) asparagine
Glycosylation358N-linked (GlcNAc...) asparagine
Glycosylation397N-linked (GlcNAc...) asparagine
Glycosylation450N-linked (GlcNAc...) asparagine
Glycosylation463N-linked (GlcNAc...) asparagine
Glycosylation469N-linked (GlcNAc...) asparagine
Glycosylation497N-linked (GlcNAc...) asparagine
Glycosylation500N-linked (GlcNAc...) asparagine
Glycosylation521N-linked (GlcNAc...) asparagine
Glycosylation549N-linked (GlcNAc...) asparagine
Glycosylation555N-linked (GlcNAc...) asparagine
Glycosylation594N-linked (GlcNAc...) asparagine
Lipidation609GPI-like-anchor amidated serine
PropeptidePRO_0000245556610-633Removed in mature form

Post-translational modification

The GPI-like anchor contains a phosphoceramide lipid group.

Keywords

PTM databases

Expression

Induction

Induced by lecithin.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain47-594PLA2c

Sequence similarities

Belongs to the lysophospholipase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    633
  • Mass (Da)
    68,144
  • Last updated
    2009-05-05 v1
  • Checksum
    277A47E29FD74796
MKTTTVACAVAGLLFSCVSGAPDPVHVEIQQRALPNAPDGYTPSTVGCPASRPTIRSAASLSPNETSWLETRRGKTTSAMKDFFNHVKIQDFDAAGYIDRHSSNSSDLPNIGIAVSGGGYRALMNGAGAIKAFDSRTPNSTSAGQLGGLLQSATYLSGLSGGSWLVGSIYINNFTTISALQTHQKGTVWQFQNSIFEGPDGGSIQILDSATYYRDISNAVSGKSDAGYPTSITDYWGRALSYQMINATNGGPSYTWSSIALTDAFQKAEMPMPLVVADGRYPGELLISSNATVYEFNPWEFGTFDPTVFGFAPLEYLGTKFNGGSVPSNESCVRGFDNVGFVMGTSSTLFNQFLLQINSTALPDWLKSVFTDILKDIGENDEDIAQYAPNPFYHFSNTTNPSAAELELDLVDGGEDLQNIPLHPLIQPERHVDVIFAVDSSADTTYSWPNGTALVATYERSLNSSGIANGTSFPAIPDQNTFVNKGLNTRPTFFGCNSSNTTGPSPLIVYLPNYPYTAYSNFSTFQPDYTEQERDSTILNGYDVVTMGNSTRDGNWSTCVGCAILSRSLERTNTNVPEICKQCFQRYCWDGSLNSTTPAGYEPVTILDSAASGIIPSISTVAMAVVFAAWTIF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF223004
EMBL· GenBank· DDBJ
AAF64038.2
EMBL· GenBank· DDBJ
Genomic DNA
AAHF01000005
EMBL· GenBank· DDBJ
EAL89914.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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