P0C5A1 · DUS29_ORYLA

Function

function

Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate (By similarity).
Involved in the modulation of AMPK and MAPK1/2 signaling pathways (By similarity).

Catalytic activity

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site137-144substrate
Active site138Phosphocysteine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentnucleus
Molecular FunctionMAP kinase phosphatase activity
Molecular Functionmyosin phosphatase activity
Molecular Functionprotein tyrosine phosphatase activity
Molecular Functionprotein tyrosine/serine/threonine phosphatase activity
Biological Processnegative regulation of MAPK cascade
Biological Processprotein dephosphorylation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity phosphatase 29
  • Alternative names
    • Dual specificity phosphatase DUPD1 (EC:3.1.3.16
      , EC:3.1.3.48
      ) . EC:3.1.3.16 (UniProtKB | ENZYME | Rhea)
      , EC:3.1.3.48 (UniProtKB | ENZYME | Rhea)

Gene names

    • Name
      dusp29
    • Synonyms
      dupd1

Organism names

  • Taxonomic identifier
  • Strain
    • Hd-rR
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Neoteleostei > Acanthomorphata > Ovalentaria > Atherinomorphae > Beloniformes > Adrianichthyidae > Oryziinae > Oryzias

Accessions

  • Primary accession
    P0C5A1

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002958881-203Dual specificity phosphatase 29

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain47-193Tyrosine-protein phosphatase

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    203
  • Mass (Da)
    23,002
  • Last updated
    2007-07-24 v1
  • MD5 Checksum
    8A0DF45075B145D32D772F92F7527DB5
MSSCVEKSRGRNPYAAVQVDPDSDYITPGTLDLEQLFWSGPTAQYAHVNQVWPRIYLGDEKTALERPALKDLGITHVLNAAVGKWNNVLTGADYYTGMNIRYLGVEADDKPTFNISQYFSQAAEFIHEALIHPVLVHCVMGRSRSATLVLAYLMIKEHLSVVDAVEHVRQRRCILPNHGFLKQLRALDIALQEEKLRLKRKDE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BAAF04042477
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

Similar Proteins

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