P0AG40 · RIBF_ECOLI
- ProteinBifunctional riboflavin kinase/FMN adenylyltransferase
- GeneribF
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids313 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.
Catalytic activity
- ATP + riboflavin = ADP + FMN + H+
Pathway
Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.
Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | FMN adenylyltransferase activity | |
Molecular Function | riboflavin kinase activity | |
Biological Process | FAD biosynthetic process | |
Biological Process | FMN biosynthetic process | |
Biological Process | riboflavin biosynthetic process | |
Biological Process | riboflavin metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameBifunctional riboflavin kinase/FMN adenylyltransferase
- Alternative names
Including 2 domains:
- Recommended nameRiboflavin kinase
- EC number
- Alternative names
- Recommended nameFMN adenylyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia
Accessions
- Primary accessionP0AG40
- Secondary accessions
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000194137 | 1-313 | Bifunctional riboflavin kinase/FMN adenylyltransferase | |||
Sequence: MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGRKRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAALTAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEGGVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQVSPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVLRKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA |
Proteomic databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | P0AG40 | aceE P0AFG8 | 2 | EBI-542969, EBI-542683 |
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length313
- Mass (Da)34,734
- Last updated2005-12-20 v1
- ChecksumC0B2EF5499CD30FE
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 108 | in Ref. 1; AAA24605 and 2; no nucleotide entry | ||||
Sequence: I → V | ||||||
Sequence conflict | 128-169 | in Ref. 1; AAA24605 and 2; no nucleotide entry | ||||
Sequence: RFGAGREGDFLLLQKAGMEYGFDITSTQTFCEGGVRISSTAV → PLALVVKAISCYYRKLAWNTASISPVRKLFAEVACASAARL | ||||||
Sequence conflict | 214 | in Ref. 1; AAA24605 and 2; no nucleotide entry | ||||
Sequence: L → P |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M10428 EMBL· GenBank· DDBJ | AAA24605.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
U00096 EMBL· GenBank· DDBJ | AAC73136.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AP009048 EMBL· GenBank· DDBJ | BAB96594.2 EMBL· GenBank· DDBJ | Genomic DNA |