P0AG40 · RIBF_ECOLI

  • Protein
    Bifunctional riboflavin kinase/FMN adenylyltransferase
  • Gene
    ribF
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

function

Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

Catalytic activity

Pathway

Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.
Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular FunctionFMN adenylyltransferase activity
Molecular Functionriboflavin kinase activity
Biological ProcessFAD biosynthetic process
Biological ProcessFMN biosynthetic process
Biological Processriboflavin biosynthetic process
Biological Processriboflavin metabolic process

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional riboflavin kinase/FMN adenylyltransferase
  • Alternative names
    • Riboflavin biosynthesis protein RibF

Including 2 domains:

  • Recommended name
    Riboflavin kinase
  • EC number
  • Alternative names
    • Flavokinase
  • Recommended name
    FMN adenylyltransferase
  • EC number
  • Alternative names
    • FAD pyrophosphorylase
    • FAD synthase

Gene names

    • Name
      ribF
    • Synonyms
      yaaC
    • Ordered locus names
      b0025, JW0023

Organism names

  • Taxonomic identifier
  • Strains
    • K12
    • K12 / MG1655 / ATCC 47076
    • K12 / W3110 / ATCC 27325 / DSM 5911
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    P0AG40
  • Secondary accessions
    • P08391
    • P75621

Proteomes

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001941371-313Bifunctional riboflavin kinase/FMN adenylyltransferase

Proteomic databases

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY P0AG40aceE P0AFG82EBI-542969, EBI-542683

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the RibF family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    313
  • Mass (Da)
    34,734
  • Last updated
    2005-12-20 v1
  • Checksum
    C0B2EF5499CD30FE
MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGRKRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAALTAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEGGVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQVSPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVLRKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict108in Ref. 1; AAA24605 and 2; no nucleotide entry
Sequence conflict128-169in Ref. 1; AAA24605 and 2; no nucleotide entry
Sequence conflict214in Ref. 1; AAA24605 and 2; no nucleotide entry

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
M10428
EMBL· GenBank· DDBJ
AAA24605.1
EMBL· GenBank· DDBJ
Genomic DNA
U00096
EMBL· GenBank· DDBJ
AAC73136.1
EMBL· GenBank· DDBJ
Genomic DNA
AP009048
EMBL· GenBank· DDBJ
BAB96594.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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