P0A9V9 · SQUU_SHIFL
- Protein3-sulfolactaldehyde reductase
- GeneyihU
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids298 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1-sulfonate (DHPS).
Catalytic activity
- (2S)-3-sulfopropanediol + NAD+ = (2S)-3-sulfolactaldehyde + NADH + H+This reaction proceeds in the backward direction.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 11-12 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: QM | ||||||
Binding site | 31 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 65 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 96 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 123 | 2,3-dihydroxypropane-1-sulfonate (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Active site | 171 | |||||
Sequence: K | ||||||
Binding site | 174-178 | 2,3-dihydroxypropane-1-sulfonate (UniProtKB | ChEBI) | ||||
Sequence: NNYMS | ||||||
Binding site | 240 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: K |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 3-sulfolactaldehyde reductase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | 6-sulfoquinovose(1-) catabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name3-sulfolactaldehyde reductase
- EC number
- Short namesSLA reductase
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Shigella
Accessions
- Primary accessionP0A9V9
- Secondary accessions
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000173066 | 1-298 | 3-sulfolactaldehyde reductase | |||
Sequence: MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKGATPAANPAQAAKDAEFIITMLPNGDLVRNVLFGENGVCEGLSTDALVIDMSTIHPLQTDKLIADMQAKGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELINAGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTTSWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGRQDWSAILEQVRVSAGMTAKVKM |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length298
- Mass (Da)31,158
- Last updated2005-07-19 v1
- Checksum74FBC8C09FA7881C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE005674 EMBL· GenBank· DDBJ | AAN45389.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE014073 EMBL· GenBank· DDBJ | AAP18811.1 EMBL· GenBank· DDBJ | Genomic DNA |