P0A397 · TFDC_BURCE
- ProteinChlorocatechol 1,2-dioxygenase
- GenetfdC
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids255 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Preferentially converts 3,5-dichlorocatechol as opposed to other chlorinated catechols. Retains diminished activity toward non-chlorinated substrates.
Catalytic activity
- 3,5-dichlorocatechol + O2 = (2E,4E)-2,4-dichloromuconate + 2 H+
Cofactor
Note: Binds 1 Fe3+ ion per subunit.
Pathway
Aromatic compound metabolism; 3-chlorocatechol degradation.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | catechol 1,2-dioxygenase activity | |
Molecular Function | chlorocatechol 1,2-dioxygenase activity | |
Molecular Function | ferric iron binding | |
Biological Process | catabolic process | |
Biological Process | catechol-containing compound metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameChlorocatechol 1,2-dioxygenase
- EC number
Gene names
Encoded on
- Plasmid pMAB1
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Betaproteobacteria > Burkholderiales > Burkholderiaceae > Burkholderia > Burkholderia cepacia complex
Accessions
- Primary accessionP0A397
- Secondary accessions
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000085091 | 1-255 | Chlorocatechol 1,2-dioxygenase | |||
Sequence: MNKRVKDVVDAIVAAVQRVLDQKEVTEAEYRTAVHYLMQVAEQRETALLCDVFFNSTVAATKARISEGSTPAIEGPYYRDDAPLVDDRLKTYDTDDHKPLLIQGTVKAVDGSVVEDVTIDVWHSTPDGKYSGFHDDIPTDFYRGKLRVGTDGSFRVRTTMPVPYQIPDQGPTGALLETMGGHSWRPAHVHFKVKAPGYETLTTQYYFEGGDWITDDCCNGVQSSLITPDIVEEGVRLMNINFVIEPARAQAGANP |
Structure
Sequence
- Sequence statusComplete
- Length255
- Mass (Da)28,283
- Last updated2005-03-15 v1
- Checksum5BCC1BC6A94B19B4
Keywords
- Technical term