P0A2J3 · SAPB_SALTY
- ProteinPeptide transport system permease protein SapB
- GenesapB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids321 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | dipeptide transmembrane transporter activity | |
Biological Process | peptide transport | |
Biological Process | protein transport |
Keywords
- Biological process
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended namePeptide transport system permease protein SapB
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionP0A2J3
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 1-8 | Cytoplasmic | ||||
Sequence: MIIFTLRR | ||||||
Transmembrane | 9-29 | Helical | ||||
Sequence: LLLLLVTLFFLTFIGFSLSYF | ||||||
Topological domain | 30-80 | Periplasmic | ||||
Sequence: TPHAPLQGASLWNAWVFWFNGLLHWDFGVSSINGQLISEQLKEVFPATMEL | ||||||
Transmembrane | 81-101 | Helical | ||||
Sequence: CILAFGFALMVGIPVGMLAGV | ||||||
Topological domain | 102-113 | Cytoplasmic | ||||
Sequence: TRSKWPDRFISA | ||||||
Transmembrane | 114-134 | Helical | ||||
Sequence: LALLGFSIPVFWLALLLTLFF | ||||||
Topological domain | 135-174 | Periplasmic | ||||
Sequence: SLTLGWLPVSGRFDLLYEVKPVTGFAIIDAWISDSPWRDE | ||||||
Transmembrane | 175-195 | Helical | ||||
Sequence: MVMSAIRHMVLPVLTLSVAPT | ||||||
Topological domain | 196-248 | Cytoplasmic | ||||
Sequence: TEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQ | ||||||
Transmembrane | 249-269 | Helical | ||||
Sequence: FSTMLTLAMITEMVFSWPGLG | ||||||
Topological domain | 270-280 | Periplasmic | ||||
Sequence: RWLIHAIRQQD | ||||||
Transmembrane | 281-301 | Helical | ||||
Sequence: YAAISAGVMVIGSLVIVVNVI | ||||||
Topological domain | 302-321 | Cytoplasmic | ||||
Sequence: SDILGAMANPLKHKEWYALR |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000060161 | 1-321 | Peptide transport system permease protein SapB | |||
Sequence: MIIFTLRRLLLLLVTLFFLTFIGFSLSYFTPHAPLQGASLWNAWVFWFNGLLHWDFGVSSINGQLISEQLKEVFPATMELCILAFGFALMVGIPVGMLAGVTRSKWPDRFISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFAIIDAWISDSPWRDEMVMSAIRHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAIRQQDYAAISAGVMVIGSLVIVVNVISDILGAMANPLKHKEWYALR |
Proteomic databases
Expression
Induction
Part of the sapA-sapB-sapC-sapD-sapF operon, RNA detected in mid-log phase cells.
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 74-302 | ABC transmembrane type-1 | ||||
Sequence: FPATMELCILAFGFALMVGIPVGMLAGVTRSKWPDRFISALALLGFSIPVFWLALLLTLFFSLTLGWLPVSGRFDLLYEVKPVTGFAIIDAWISDSPWRDEMVMSAIRHMVLPVLTLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLIHAIRQQDYAAISAGVMVIGSLVIVVNVIS |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length321
- Mass (Da)36,111
- Last updated2005-03-15 v1
- Checksum8A84AF71282E95F9
Features
Showing features for sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Sequence conflict | 97-98 | in Ref. 1; CAA52285 | ||||
Sequence: ML → TV | ||||||
Sequence conflict | 169 | in Ref. 1; CAA52285 | ||||
Sequence: S → C |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X74212 EMBL· GenBank· DDBJ | CAA52285.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE006468 EMBL· GenBank· DDBJ | AAL20610.1 EMBL· GenBank· DDBJ | Genomic DNA |