Pregnancy Zone Protein (PZP) is significantly upregulated in the decidua of recurrent and spontaneous miscarriage and negatively correlated to Glycodelin A (GdA).
the findings of this study provide evidence that inhibiting these targets affects the expression of glycodelin and its immunosuppressive effect in nonsmall cell lung cancer tumours. Moreover understanding the regulation of glycodelin expression may lead to the development of novel therapeutic approaches with which to weaken the immune system defence of NSCLC tumours in the future
The results from the present study suggested that PP14 may be a novel potential biomarker for PPROM and may be developed into a lateral flow assay for bedside application to rapidly diagnose PPROM.
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