Characterization of a human multilineage-colony-stimulating factor cDNA clone identified by a conserved noncoding sequence in mouse interleukin- 3.Dorssers L., Burger H., Bot F., Delwel R., Geurts van Kessel A.H.M., Loewenberg B., Wagemaker G.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGene 55:115-124 (1987)Cited in1
Isolation and characterization of an expressible cDNA encoding human IL-3. Induction of IL-3 mRNA in human T cell clones.Otsuka T., Miyajima A., Brown N., Otsu K., Abrams J., Saeland S., Caux C., de Waal Malefijt R., de Vries J.[...], Yokota T.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 140:2288-2295 (1988)Cited in1
Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3.Yang Y.-C., Ciarletta A.B., Temple P.A., Chung M.P., Kovacic S., Witek-Giannotti J.S., Leary A.C., Kriz R., Donahue R.E.[...], Clark S.C.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 47:3-10 (1986)Cited in2
No title available.SeattleSNPs variation discovery resourceCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS HIS-15 AND SER-27CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JUN-2001)Cited in23
The DNA sequence and comparative analysis of human chromosome 5.Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G.[...], Rubin E.M.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 431:268-274 (2004)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT SER-27CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Molecular characterization of colony-stimulating factors and their receptors: human interleukin-3.Urdal D.L., Price V., Sassenfeld H.M., Cosman D., Gillis S., Park L.S.Cited forNUCLEOTIDE SEQUENCE OF 20-152, VARIANT SER-27CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAnn. N. Y. Acad. Sci. 554:167-176 (1989)Cited in1
Regulation of interleukin 3 gene induction in normal human T cells.Guba S.C., Stella G., Turka L.A., June C.H., Thompson C.B., Emerson S.G.View abstractCited forFUNCTION, INDUCTION BY T-CELL RECEPTOR/CD3 PATHWAYCategoriesFunction, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Clin. Invest. 84:1701-1706 (1989)Cited in1
Comparison of mechanisms of IL-3 induced histamine release and IL-3 priming effect on human basophils.Okayama Y., Begishvili T.B., Church M.K.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCClin. Exp. Allergy 23:901-910 (1993)Cited in1
IL-3 acts directly on osteoclast precursors and irreversibly inhibits receptor activator of NF-kappa B ligand-induced osteoclast differentiation by diverting the cells to macrophage lineage.Khapli S.M., Mangashetti L.S., Yogesha S.D., Wani M.R.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Immunol. 171:142-151 (2003)Cited in1Mapped to3
The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors.Alzheimer's Disease Neuroimaging InitiativeLuo X.J., Li M., Huang L., Nho K., Deng M., Chen Q., Weinberger D.R., Vasquez A.A., Rijpkema M.[...], Su B.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS ONE 7:e50375-e50375 (2012)Cited in1Mapped to2
Interleukin-3 Prevents Cellular Death Induced by Oxidative Stress in HEK293 Cells.Lopez C., Zamorano P., Teuber S., Salas M., Otth C., Hidalgo M.A., Concha I., Zambrano A.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Cell. Biochem. 118:1330-1340 (2017)Cited in1Mapped to2
Interleukin 3-induced GITR promotes the activation of human basophils.Hong L., Tang Y., Pan S., Xu M., Shi Y., Gao S., Sui C., He C., Zheng K.[...], Wang H.View abstractCited forFUNCTION IN ACTIVATION OF BASOPHILSCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCytokine 136:155268-155268 (2020)Cited in1Mapped to5
Three-dimensional solution structure and backbone dynamics of a variant of human interleukin-3.Feng Y., Klein B.K., McWherter C.A.View abstractCited forSTRUCTURE BY NMRCategoriesStructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Mol. Biol. 259:524-541 (1996)Cited in1
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.Broughton S.E., Hercus T.R., Nero T.L., Kan W.L., Barry E.F., Dottore M., Cheung Tung Shing K.S., Morton C.J., Dhagat U.[...], Parker M.W.View abstractCited forX-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 31-152, DISULFIDE BONDS, INTERACTION WITH IL3RA, FUNCTIONCategoriesPTM / Processing, Function, Interaction, StructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Commun. 9:386-386 (2018)Cited in2
Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation.Gu H., Pratt J.C., Burakoff S.J., Neel B.G.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCMol. Cell 2:729-740 (1998)Cited in2Mapped to27
Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors.Guthridge M.A., Stomski F.C., Thomas D., Woodcock J.M., Bagley C.J., Berndt M.C., Lopez A.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCStem Cells 16:301-313 (1998)Mapped to8
Familial eosinophilia maps to the cytokine gene cluster on human chromosomal region 5q31-q33.Rioux J.D., Stone V.A., Daly M.J., Cargill M., Green T., Nguyen H., Nutman T., Zimmerman P.A., Tucker M.A.[...], Lin A.Y.View abstractAnnotationNot Associated with OTHER: Eosinophilia.CategoriesDisease & VariantsSourceGAD:142630PubMedEurope PMCAm J Hum Genet 63:1086-1094 (1998)Mapped to4
In vitro interaction between STAT 5 and JAK 2; dependence upon phosphorylation status of STAT 5 and JAK 2.Flores-Morales A., Pircher T.J., Silvennoinen O., Gustafsson J.A., Sanchez-Gomez M., Norstedt G., Haldosen L.A., Wood T.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCMol Cell Endocrinol 138:1-10 (1998)Mapped to10
Identification of a Cys motif in the common beta chain of the interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 receptors essential for disulfide-linked receptor heterodimerization and activation of all three receptors.Stomski F.C., Woodcock J.M., Zacharakis B., Bagley C.J., Sun Q., Lopez A.F.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCJ Biol Chem 273:1192-1199 (1998)Mapped to8
SHP1 and SHP2 protein-tyrosine phosphatases associate with betac after interleukin-3-induced receptor tyrosine phosphorylation. Identification of potential binding sites and substrates.Bone H., Dechert U., Jirik F., Schrader J.W., Welham M.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCJ Biol Chem 272:14470-14476 (1997)Mapped to10
Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop.Feng J., Witthuhn B.A., Matsuda T., Kohlhuber F., Kerr I.M., Ihle J.N.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCMol Cell Biol 17:2497-2501 (1997)Mapped to24
Purification and molecular cloning of SH2- and SH3-containing inositol polyphosphate-5-phosphatase, which is involved in the signaling pathway of granulocyte-macrophage colony-stimulating factor, erythropoietin, and Bcr- Abl.Odai H., Sasaki K., Iwamatsu A., Nakamoto T., Ueno H., Yamagata T., Mitani K., Yazaki Y., Hirai H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCBlood 89:2745-2756 (1997)Cited in2Mapped to33
Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP.Lamkin T.D., Walk S.F., Liu L., Damen J.E., Krystal G., Ravichandran K.S.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCJ. Biol. Chem. 272:10396-10401 (1997)Cited in2Mapped to17
A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation.Behrmann I., Janzen C., Gerhartz C., Schmitz-Van de Leur H., Hermanns H., Heesel B., Graeve L., Horn F., Tavernier J., Heinrich P.C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-450059PubMedEurope PMCJ Biol Chem 272:5269-5274 (1997)Mapped to19