The repressing activity of leucine-responsive transcriptional regulator (Leu3) on GABA-specific transport protein UGA4 and GABA Aminotransferase UGA1 occurs through GATA Transcription Factors Dal80. Leu3 facilitates interactions between Dal80 with DNA. However when the expression of GATA factors is null or negligible Leu3 functions as an activator.
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