Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity.Ullrich A., Gray A., Tam A.W., Yang-Feng T., Tsubokawa M., Collins C., Henzel W., Bon T.L., Kathuria S.[...], Fujita-Yamaguchi Y.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 31-56; 446-453; 503-524; 561-579; 668-672 AND 721-729TissuePlacentaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 5:2503-2512 (1986)Cited in1
Insulin-like growth factor I receptor gene structure.Abbot A.M., Bueno R., Pedrini M.T., Murray J.M., Smith R.J.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 267:10759-10763 (1992)Cited in1
No title available.Nagase T., Kikuno R.F., Yamakawa H., Ohara O.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueFetal brainCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (FEB-2008)Cited in1
No title available.NIEHS SNPs programCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS MET-388 AND HIS-605CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JUN-2003)Cited in14
Analysis of the DNA sequence and duplication history of human chromosome 15.Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K., Whittaker C.A., Kamal M., Chang J.L.[...], Nusbaum C.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 440:671-675 (2006)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Analysis of the human type I insulin-like growth factor receptor promoter region.Cooke D.W., Bankert L.A., Roberts C.T. Jr., Leroith D., Casella S.J.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-31CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. Biophys. Res. Commun. 177:1113-1120 (1991)Cited in1
Characterization of human placental insulin-like growth factor-I/insulin hybrid receptors by protein microsequencing and purification.Kasuya J., Paz I.B., Maddux B.A., Goldfine I.D., Hefta S.A., Fujita-Yamaguchi Y.View abstractCited forPROTEIN SEQUENCE OF 31-45 AND 741-750, FUNCTION, FORMATION OF A HYBRID RECEPTOR WITH INSRTissuePlacentaCategoriesFunction, SequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochemistry 32:13531-13536 (1993)Cited in2
A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.Lee S.-T., Strunk K.M., Spritz R.A.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA] OF 1137-1193, TISSUE SPECIFICITYTissueMelanocyteCategoriesSequences, ExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCOncogene 8:3403-3410 (1993)Cited in7
Interaction of the alpha beta dimers of the insulin-like growth factor I receptor is required for receptor autophosphorylation.Tollefsen S.E., Stoszek R.M., Thompson K.View abstractCited forFUNCTION, SUBUNIT, AUTOPHOSPHORYLATIONCategoriesFunction, PTM / Processing, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochemistry 30:48-54 (1991)Cited in1
Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity.Soos M.A., Field C.E., Siddle K.View abstractCited forFUNCTION, FORMATION OF A HYBRID RECEPTOR WITH INSRCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. J. 290:419-426 (1993)Cited in2Mapped to2
Role of tyrosine kinase activity in signal transduction by the insulin- like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3).Kato H., Faria T.N., Stannard B., Roberts C.T. Jr., LeRoith D.View abstractCited forFUNCTION, CATALYTIC ACTIVITY, AUTOPHOSPHORYLATIONCategoriesFunction, PTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 268:2655-2661 (1993)Cited in1
Non-SH2 domains within insulin receptor substrate-1 and SHC mediate their phosphotyrosine-dependent interaction with the NPEY motif of the insulin- like growth factor I receptor.Craparo A., O'Neill T.J., Gustafson T.A.View abstractCited forINTERACTION WITH IRS1; SHC1 AND PIK3R1, MUTAGENESIS OF TYR-980 AND LYS-1033, PHOSPHORYLATION AT TYR-980CategoriesPTM / Processing, Disease & Variants, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 270:15639-15643 (1995)Cited in4Mapped to4
Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting.Bailyes E.M., Nave B.T., Soos M.A., Orr S.R., Hayward A.C., Siddle K.View abstractCited forFORMATION OF A HYBRID RECEPTOR WITH INSR, TISSUE SPECIFICITYCategoriesExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. J. 327:209-215 (1997)Cited in2
14-3-3 proteins interact with the insulin-like growth factor receptor but not the insulin receptor.Furlanetto R.W., Dey B.R., Lopaczynski W., Nissley S.P.View abstractCited forINTERACTION WITH 14-3-3 PROTEINSCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. J. 327:765-771 (1997)Cited in1Mapped to3
Distribution of insulin/insulin-like growth factor-I hybrid receptors in human tissues.Federici M., Porzio O., Zucaro L., Fusco A., Borboni P., Lauro D., Sesti G.View abstractCited forFORMATION OF A HYBRID RECEPTOR WITH INSR, TISSUE SPECIFICITYCategoriesExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Endocrinol. 129:121-126 (1997)Cited in2
Interaction of human suppressor of cytokine signaling (SOCS)-2 with the insulin-like growth factor-I receptor.Dey B.R., Spence S.L., Nissley P., Furlanetto R.W.View abstractCited forINTERACTION WITH SOCS1 AND SOCS2CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 273:24095-24101 (1998)Cited in3
beta-arrestins regulate mitogenic signaling and clathrin-mediated endocytosis of the insulin-like growth factor I receptor.Lin F.-T., Daaka Y., Lefkowitz R.J.View abstractCited forINTERACTION WITH ARRB1 AND ARRB2CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 273:31640-31643 (1998)Cited in3
The IGF-I receptor in cancer research.Baserga R.View abstractCited forFUNCTION IN CANCERCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCExp. Cell Res. 253:1-6 (1999)Cited in1Mapped to4
Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis.Wang J., Dai H., Yousaf N., Moussaif M., Deng Y., Boufelliga A., Swamy O.R., Leone M.E., Riedel H.View abstractCited forINTERACTION WITH GRB10, MUTAGENESIS OF TYR-980; TYR-1280; TYR-1281 AND TYR-1346CategoriesDisease & Variants, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 19:6217-6228 (1999)Cited in6Mapped to1
Suppressor of cytokine signaling (SOCS)-3 protein interacts with the insulin-like growth factor-I receptor.Dey B.R., Furlanetto R.W., Nissley P.View abstractCited forINTERACTION WITH SOCS3CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. Biophys. Res. Commun. 278:38-43 (2000)Cited in2
Autophosphorylation of the insulin-like growth factor I receptor cytoplasmic domain.Lopaczynski W., Terry C., Nissley P.View abstractCited forAUTOPHOSPHORYLATIONCategoriesPTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. Biophys. Res. Commun. 279:955-960 (2000)Cited in1
Mechanism of STAT3 activation by insulin-like growth factor I receptor.Zong C.S., Chan J., Levy D.E., Horvath C., Sadowski H.B., Wang L.H.View abstractCited forFUNCTION IN ACTIVATION OF STAT3CategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 275:15099-15105 (2000)Cited in1
Expression of the type 1 insulin-like growth factor receptor is up- regulated in primary prostate cancer and commonly persists in metastatic disease.Hellawell G.O., Turner G.D., Davies D.R., Poulsom R., Brewster S.F., Macaulay V.M.View abstractCited forTISSUE SPECIFICITYCategoriesExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCancer Res. 62:2942-2950 (2002)Cited in1
Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved.Pandini G., Frasca F., Mineo R., Sciacca L., Vigneri R., Belfiore A.View abstractCited forFUNCTION, FORMATION OF A HYBRID RECEPTOR WITH INSRCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 277:39684-39695 (2002)Cited in2Mapped to38