P07666 · SRYA_DROME

Function

function

Required for the cellularization of the syncytial blastoderm embryo. Involved in the localization of the actin filaments just prior to and during plasma membrane invagination. Sry-alpha together with nullo and bnk may provide auxiliary functions, by acting both to stabilize a large and dynamic microfilament structure and regulate its functions.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentadherens junction
Cellular Componentcatenin complex
Cellular Componentcleavage furrow
Cellular Componentcytosol
Cellular Componentplasma membrane
Molecular Functionactin filament binding
Molecular Functionbeta-catenin binding
Biological Processactin filament organization
Biological Processcell migration
Biological Processcell-cell adhesion
Biological Processcellularization

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serendipity locus protein alpha

Gene names

    • Name
      Sry-alpha
    • Synonyms
      Sry-a
    • ORF names
      CG17957

Organism names

  • Taxonomic identifier
  • Strains
    • Oregon-R
    • Berkeley
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Diptera > Brachycera > Muscomorpha > Ephydroidea > Drosophilidae > Drosophila > Sophophora

Accessions

  • Primary accession
    P07666
  • Secondary accessions
    • Q9VAB4

Proteomes

Organism-specific databases

Subcellular Location

Cytoplasm
Cell membrane
; Peripheral membrane protein
Note: Inner membrane-associated and cytoplasmic. Colocalizes with the structural transitions in the microfilament network during cellularization.

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000721971-530Serendipity locus protein alpha

Proteomic databases

Expression

Tissue specificity

Transient expression in blastoderm from nuclear cycle 11 to the onset of gastrulation.

Developmental stage

Transcript levels rise steadily during syncytial stages to reach a peak in early cycle 14 and then decline rapidly during cellularization.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence

  • Sequence status
    Complete
  • Length
    530
  • Mass (Da)
    59,385
  • Last updated
    1988-04-01 v1
  • Checksum
    EC576378256193FB
MEQLLAQLHTCSELIAEGYSSTGNIGWLNEFCATFLDFASDLKARLPEVAPSGANLDVETIFLCLTQVVTCITHLERTISMEAPHMTRQHFLDRLDWCLRRLLVSLTQLEGNVTPVKNLEDHSFVELMDLALDHLDDYMEKLAQQRNNSLHILEESFTEDTYQLASIVNHIVRHALAFANVAIHSDKKALTALCETLLAECATFHEEAGEPNSGHRKLEALSLERALYALESFLNEALLHLLFVSLIDLENASVEKLKDALQRDPAGAQELISAFDTNMDRIQQIGVLAIAFSQDIKTKTIVRSCLASLESLDACIVPALQLPESTSSAHHAEVLQEHFNQELLIFRNVIHEIIDSCSLINNYLDMLGERIHVQDKSHLKLIVQRGGVVVDHFRLPVNYSGLSEDGKRVHKDLILILRECQAVVNLDVPVDPKRIVKRLKILYSVLAKLRDLICRDNLEPDSSVASEAQVPSSATRTFVRSSRSFGKRHRSFVKQTGNCSVFGPQDSLAESGHSESDLISFQITEILRLD

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A126GV23A0A126GV23_DROMESry-alpha530

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
X03121
EMBL· GenBank· DDBJ
CAA26897.1
EMBL· GenBank· DDBJ
Genomic DNA
AE014297
EMBL· GenBank· DDBJ
AAF56999.1
EMBL· GenBank· DDBJ
Genomic DNA
AY071374
EMBL· GenBank· DDBJ
AAL48996.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp