P06795 · MDR1B_MOUSE
- ProteinATP-dependent translocase ABCB1
- GeneAbcb1b
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids1276 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Publications for P06795
Placental P-glycoprotein deficiency enhances susceptibility to chemically induced birth defects in mice.
- CategoriesSequences, Phenotypes & Variants
- SourceMGI: 97568
Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 97568
Pharmacological insights from P-glycoprotein knockout mice.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 97568
- PubMed
- Europe PMC
- Int J Clin Pharmacol Ther 36:9-13 ()
Mapped toBcl-2 and mdr-1 gene expression during doxorubicin-induced apoptosis in murine leukemic P388 and P388/R84 cells.
- CategoriesFunction
- SourceMGI: 97568
- PubMed
- Europe PMC
- Anticancer Res 17:3369-3376 ()
Mapped toGenetic dissection of the function of mammalian P-glycoproteins.
- CategoriesFunction
- SourceMGI: 97568
Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins.
- CategoriesFunction, Phenotypes & Variants
- SourceMGI: 97568
Co-ordinate regulation of the cystic fibrosis and multidrug resistance genes in cystic fibrosis knockout mice.
- CategoriesExpression
- SourceMGI: 97568
Genetic mapping of 18S ribosomal RNA-related loci to mouse chromosomes 5, 6, 9, 12, 17, 18, 19, and X.
- CategoriesSequences
- SourceMGI: 97568
The multidrug resistance P-glycoprotein modulates cell regulatory volume decrease.
- CategoriesFunction
- SourceMGI: 97568
Transfer of the MDR1 gene into haematopoietic cells.
- CategoriesFunction, Sequences
- SourceMGI: 97568
What have we learnt thus far from mice with disrupted P-glycoprotein genes?
- CategoriesFunction
- SourceMGI: 97568
Expression of P-glycoprotein, encoded by MDR 1 gene, a metabolically active efflux pump in murine mast cells.
- CategoriesExpression
- SourceMGI: 97568
[Relationship between amplicon composition and cytologic type of structures containing amplified DNA in murine P388 cells with multiple drug resistance].
- CategoriesSequences
- SourceMGI: 97568
- PubMed
- Europe PMC
- Genetika 31:1449-1451 ()
Mapped toGenetic mapping of the mouse gene encoding dipeptidyl aminopeptidase-like proteins.
- CategoriesSequences
- SourceMGI: 97568
Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941.
- CategoriesPhenotypes & Variants
- SourceMGI: 97568
Specific targeting and killing activities of anti-P-glycoprotein monoclonal antibody MRK16 directed against intrinsically multidrug- resistant human colorectal carcinoma cell lines in the nude mouse model.
- CategoriesFunction
- SourceMGI: 97568
- PubMed
- Europe PMC
- Cancer Res 53:5475-5482 ()
Mapped toExpression of an mdr gene is associated with a new form of resistance to dexamethasone-induced apoptosis.
- CategoriesSequences
- SourceMGI: 97568
Mapping of a rat multidrug resistance gene by fluorescence in situ hybridization.
- CategoriesSequences
- SourceMGI: 97568
Structure, genetic mapping, and expression of the mouse Hgf/scatter factor gene.
- CategoriesSequences
- SourceMGI: 97568