P06308 · OVUH_LYMST
- ProteinOvulation prohormone
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids259 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
CDCH induces ovulation and egg-mass production; it may also stimulate synthesis of secretory products in the female accessory sex glands and affect neurons in the neuronal circuits controlling locomotion and feeding.
Calfluxin is involved in the influx of calcium into mitochondria of the albumen gland.
CDCA (or alpha-CDCP) triggers the electrical activity of the caudodorsal cells (CDCS).
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | extracellular region | |
Molecular Function | hormone activity | |
Biological Process | neuropeptide signaling pathway |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameOvulation prohormone
- Cleaved into 7 chains
Organism names
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Gastropoda > Heterobranchia > Euthyneura > Panpulmonata > Hygrophila > Lymnaeoidea > Lymnaeidae > Lymnaea
Accessions
- Primary accessionP06308
- Secondary accessions
Subcellular Location
PTM/Processing
Features
Showing features for signal, propeptide, peptide, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-34 | |||||
Sequence: MKMSGLLSKPDYGVVGIVFTVVFCCWCSSSTTHA | ||||||
Propeptide | PRO_0000001914 | 35-102 | ||||
Sequence: LSIAEPGRDRYDKRSPTGHGVEVVESGEDYGSNRPQPVYGDEDEEDSADVYVGSDESSSGEKTRLTAA | ||||||
Peptide | PRO_0000001915 | 105-109 | Beta-3-CDCP | |||
Sequence: RLRFN | ||||||
Peptide | PRO_0000001916 | 112-116 | Beta-2-CDCP | |||
Sequence: RLRAS | ||||||
Peptide | PRO_0000001917 | 119-123 | Beta-1-CDCP | |||
Sequence: RLRFH | ||||||
Peptide | PRO_0000001918 | 126-139 | Calfluxin | |||
Sequence: RVDSADESNDDGFD | ||||||
Peptide | PRO_0000001919 | 144-152 | Alpha-CDCP | |||
Sequence: EPRLRFHDV | ||||||
Peptide | PRO_0000001920 | 156-178 | X-CDCP | |||
Sequence: SATAEEGSENAEIEESHLGNSRS | ||||||
Propeptide | PRO_0000001921 | 181-195 | ||||
Sequence: SAGSAPSSANEVQRS | ||||||
Peptide | PRO_0000001922 | 198-233 | Ovulation hormone | |||
Sequence: LSITNDLRAIADSYLYDQHKLRERQEENLRRRFLEL | ||||||
Modified residue | 233 | Leucine amide | ||||
Sequence: L | ||||||
Propeptide | PRO_0000001923 | 237-259 | ||||
Sequence: GSAFFDHIPIIFGEPQYDYQPFK |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for region, repeat, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 42-103 | Disordered | ||||
Sequence: RDRYDKRSPTGHGVEVVESGEDYGSNRPQPVYGDEDEEDSADVYVGSDESSSGEKTRLTAAK | ||||||
Repeat | 119-123 | |||||
Sequence: RLRFH | ||||||
Region | 119-150 | 2 X 5 AA repeats of R-L-R-F-H | ||||
Sequence: RLRFHKRRVDSADESNDDGFDRKAREPRLRFH | ||||||
Repeat | 146-150 | |||||
Sequence: RLRFH | ||||||
Compositional bias | 149-176 | Basic and acidic residues | ||||
Sequence: FHDVRKRSATAEEGSENAEIEESHLGNS | ||||||
Region | 149-197 | Disordered | ||||
Sequence: FHDVRKRSATAEEGSENAEIEESHLGNSRSRRSAGSAPSSANEVQRSKR | ||||||
Compositional bias | 177-197 | Polar residues | ||||
Sequence: RSRRSAGSAPSSANEVQRSKR |
Sequence similarities
Belongs to the molluscan ELH family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length259
- Mass (Da)29,613
- Last updated1991-05-01 v2
- Checksum6EF26D5A29ADC4FE
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 149-176 | Basic and acidic residues | ||||
Sequence: FHDVRKRSATAEEGSENAEIEESHLGNS | ||||||
Compositional bias | 177-197 | Polar residues | ||||
Sequence: RSRRSAGSAPSSANEVQRSKR | ||||||
Sequence conflict | 217 | in Ref. 2; AA sequence | ||||
Sequence: K → W |
Keywords
- Technical term