P05417 · UCRI_PARDE
- ProteinUbiquinol-cytochrome c reductase iron-sulfur subunit
- GenepetA
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids190 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score4/5
Function
function
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
Miscellaneous
The Rieske protein is a high potential 2Fe-2S protein.
Catalytic activity
- a quinol + 2 Fe(III)-[cytochrome c](out) = a quinone + 2 Fe(II)-[cytochrome c](out) + 2 H+(out)
Cofactor
Note: Binds 1 [2Fe-2S] cluster per subunit.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 132 | [2Fe-2S] cluster (UniProtKB | ChEBI) | |||
Binding site | 134 | [2Fe-2S] cluster (UniProtKB | ChEBI) | |||
Binding site | 152 | [2Fe-2S] cluster (UniProtKB | ChEBI) | |||
Binding site | 155 | [2Fe-2S] cluster (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | 2 iron, 2 sulfur cluster binding | |
Molecular Function | metal ion binding | |
Molecular Function | ubiquinol-cytochrome-c reductase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameUbiquinol-cytochrome c reductase iron-sulfur subunit
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Rhodobacterales > Paracoccaceae > Paracoccus
Accessions
- Primary accessionP05417
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 18-39 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000127761 | 1-190 | Ubiquinol-cytochrome c reductase iron-sulfur subunit | ||
Disulfide bond | 137↔154 | ||||
Keywords
- PTM
Interaction
Subunit
The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.
Structure
Sequence
- Sequence statusComplete
- Length190
- Mass (Da)20,300
- Last updated1988-11-01 v1
- MD5 Checksum12E188F002E1C0B9D03DC1EEE9418513
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
M17522 EMBL· GenBank· DDBJ | AAA25571.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
X05799 EMBL· GenBank· DDBJ | CAA29243.1 EMBL· GenBank· DDBJ | Genomic DNA |