P03847 · COPB2_ECOLX

  • Protein
    Replication regulatory protein repA2
  • Gene
    repA2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Predicted
  • Annotation score
    2/5

Function

function

This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein RepA.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular FunctionDNA binding
Biological Processplasmid maintenance

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Replication regulatory protein repA2
  • Alternative names
    • Protein CopB

Gene names

    • Name
      repA2
    • Synonyms
      copB

Encoded on

  • Plasmid IncFII R100 (NR1)
  • Plasmid R6-5
  • Plasmid IncFVI pSU212

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    P03847
  • Secondary accessions
    • P13947

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000682911-84Replication regulatory protein repA2

Structure

Family & Domains

Features

Showing features for compositional bias, region.

TypeIDPosition(s)Description
Compositional bias1-16Polar residues
Region1-31Disordered

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    84
  • Mass (Da)
    9,438
  • Last updated
    1994-02-01 v2
  • Checksum
    ADC3442D128E2C81
MSQTENAVTSSSGAKRAYRKGNPLSDAEKQRLSVARKRASFKEVKVFLEPKYKAMLMQMCHEDGLTQAEVLTALIKSEAQKRCM

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias1-16Polar residues
Sequence conflict3in Ref. 2; AAA26065
Sequence conflict77-84in Ref. 2; AAA26065
Sequence conflict81-84in Ref. 1

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
J01762
EMBL· GenBank· DDBJ
AAA92255.1
EMBL· GenBank· DDBJ
Genomic DNA
M26840
EMBL· GenBank· DDBJ
AAA26065.1
EMBL· GenBank· DDBJ
Genomic DNA
V00318
EMBL· GenBank· DDBJ
CAA23608.1
EMBL· GenBank· DDBJ
Genomic DNA
M18273
EMBL· GenBank· DDBJ
AAA88332.1
EMBL· GenBank· DDBJ
Genomic DNA
X02302
EMBL· GenBank· DDBJ
CAA26165.1
EMBL· GenBank· DDBJ
Genomic DNA
X55895
EMBL· GenBank· DDBJ
CAA39380.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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