P03515 · NCAP_PTPV

Function

function

Encapsidates the genomic RNA, protecting it from nucleases. Displays high affinity for single-stranded nucleic acid. The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein. The ribonucleoprotein has a non-helical structure (By similarity).
Serves as template for viral transcription and replication. After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).

Features

Showing features for site.

124320406080100120140160180200220240
TypeIDPosition(s)Description
Site29RNA-binding
Site32RNA-binding
Site65RNA-binding
Site66RNA-binding
Site98RNA-binding
Site105RNA-binding

GO annotations

AspectTerm
Cellular Componenthelical viral capsid
Cellular Componenthost cell endoplasmic reticulum-Golgi intermediate compartment
Cellular Componenthost cell Golgi apparatus
Cellular Componenthost cell nucleus
Cellular Componentribonucleoprotein complex
Cellular Componentviral nucleocapsid
Molecular FunctionRNA binding

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoprotein
  • Alternative names
    • Nucleocapsid protein (Protein N)

Gene names

    • Name
      N

Organism names

Accessions

  • Primary accession
    P03515

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002219941-243Nucleoprotein

Interaction

Subunit

Homodimer. Homohexamer; ring-shaped, necessary to form the nucleocapsid (By similarity).
Homopentamers; opened pentamers in solution (By similarity).
Binds to viral genomic RNA (By similarity).
Interacts with glycoprotein Gn; this interaction allows packaging of nucleocapsids into virions (By similarity).

Structure

3D structure databases

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    243
  • Mass (Da)
    26,911
  • Last updated
    1986-07-21 v1
  • Checksum
    0CE34C9E1DBA0589
MSYEEIAVQFASESIDEQTVAGWVTDFAYQGFDAKRVIALVKDRGGEDWKQDVKKMIVLSLTRGNKPNKMILKMSDKGKAMVNELVLKYKLKSGNPSRDDLTLSRITAAFAGWTCQAADYVQEYLPVTGRAMDAISSSYPRAMMHPSFAGLIDQELPADVFSEITQAHCLFMIQFSKTINPSLRGLSKDEIVSSFERPMQAAISSTFLTSANRRAMLKTLGIINDNLKPSSSTVSAAKVFRSL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
K02736
EMBL· GenBank· DDBJ
AAA47114.1
EMBL· GenBank· DDBJ
Genomic RNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp