Sequence of interrupted and uninterrupted mRNAs and cloned DNA coding for the two overlapping nonstructural proteins of influenza virus.Lamb R.A., Lai C.-J.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC RNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 21:475-485 (1980)Cited in4
Complete genome sequencing and analysis of selected influenza virus vaccine strains spanning six decades (1933-1999).Mbawuike I.N., Zhang Y., Yamada R.E., Nino D., Bui H.-H., Sette A., Couch R.B.Cited forNUCLEOTIDE SEQUENCE [GENOMIC RNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (APR-2006)Cited in24
Two functional domains of the influenza virus NS1 protein are required for regulation of nuclear export of mRNA.Qian X.Y., Alonso-Caplen F., Krug R.M.View abstractCited forMUTAGENESIS OF 7-SER-SER-8; 19-ARG-PHE-20; 31-PRO-PHE-32; 35-ARG--ARG-38; 39-ASP-GLN-40; 48-SER-THR-49; 62-LYS-GLN-63; 73-SER-ASP-74; 87-SER-ARG-88; 99-SER-ARG-100; 116-CYS-ILE-117; 134-PHE--VAL-136; LEU-141; LEU-144; LEU-146; 150-PHE-THR-151; 160-ILE-SER-161; 175-LYS-ASN-176; 199-GLN-ARG-200; 205-SER-SER-206 AND 219-LYS-LYS-221CategoriesPhenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Virol. 68:2433-2441 (1994)Cited in1
The influenza virus NS1 protein forms multimers in vitro and in vivo.Nemeroff M.E., Qian X.Y., Krug R.M.View abstractCited forDIMERIZATIONCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCVirology 212:422-428 (1995)Cited in1
The RNA-binding and effector domains of the viral NS1 protein are conserved to different extents among influenza A and B viruses.Wang W., Krug R.M.View abstractCited forRNA-BINDINGCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCVirology 223:41-50 (1996)Cited in2
Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs.Nemeroff M.E., Barabino S.M.L., Li Y., Keller W., Krug R.M.View abstractCited forFUNCTION, INTERACTION WITH HUMAN CPSF4CategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 1:991-1000 (1998)Cited in2Mapped to7
Biochemical and genetic evidence for complex formation between the influenza A virus NS1 protein and the interferon-induced PKR protein kinase.Tan S.L., Katze M.G.View abstractCited forINTERACTION WITH HUMAN EIF2AK2/PKRCategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Interferon Cytokine Res. 18:757-766 (1998)Cited in2
Regulation of a nuclear export signal by an adjacent inhibitory sequence: the effector domain of the influenza virus NS1 protein.Li Y., Yamakita Y., Krug R.M.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 95:4864-4869 (1998)Cited in1
Influenza A virus NS1 protein targets poly(A)-binding protein II of the cellular 3'-end processing machinery.Chen Z., Li Y., Krug R.M.View abstractCited forINTERACTION WITH HUMAN PABPN1CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCEMBO J. 18:2273-2283 (1999)Cited in2Mapped to7
The 3'-end-processing factor CPSF is required for the splicing of single- intron pre-mRNAs in vivo.Li Y., Chen Z.Y., Wang W., Baker C.C., Krug R.M.View abstractCited forMUTAGENESIS OF 186-GLU-TRP-187; 201-PHE--TRP-203 AND 212-PRO-PRO-213CategoriesPhenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCRNA 7:920-931 (2001)Cited in1Mapped to1
Intracellular warfare between human influenza viruses and human cells: the roles of the viral NS1 protein.Krug R.M., Yuan W., Noah D.L., Latham A.G.Cited forREVIEWSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCVirology 309:181-189 (2003)Cited in58
The CPSF30 binding site on the NS1A protein of influenza A virus is a potential antiviral target.Twu K.Y., Noah D.L., Rao P., Kuo R.L., Krug R.M.View abstractCited forFUNCTION, INTERACTION WITH HOST CPSF4CategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Virol. 80:3957-3965 (2006)Cited in1
A novel RNA-binding motif in influenza A virus non-structural protein 1.Chien C.Y., Tejero R., Huang Y., Zimmerman D.E., Rios C.B., Krug R.M., Montelione G.T.View abstractCited forSTRUCTURE BY NMR OF 1-73CategoriesStructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Struct. Biol. 4:891-895 (1997)Cited in1
Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein.Liu J., Lynch P.A., Chien C.Y., Montelione G.T., Krug R.M., Berman H.M.View abstractCited forX-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 1-72CategoriesStructureSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Struct. Biol. 4:896-899 (1997)Cited in1
Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1.Qin S., Liu Y., Tempel W., Eram M.S., Bian C., Liu K., Senisterra G., Crombet L., Vedadi M., Min J.View abstractCategoriesStructureSourcePDB: 4NW2, PDB: 4O45PubMedEurope PMCNat Commun 5:3952-3952 (2014)Cited in1Mapped to8
Structure homology and interaction redundancy for discovering virus-host protein interactions.de Chassey B., Meyniel-Schicklin L., Aublin-Gex A., Navratil V., Chantier T., Andre P., Lotteau V.View abstractCategoriesInteractionSourceIntAct: P03495PubMedEurope PMCEMBO Rep 14:938-944 (2013)Mapped to15
Viral immune modulators perturb the human molecular network by common and unique strategies.Pichlmair A., Kandasamy K., Alvisi G., Mulhern O., Sacco R., Habjan M., Binder M., Stefanovic A., Eberle C.A.[...], Superti-Furga G.View abstractCategoriesInteractionSourceIntAct: P03495PubMedEurope PMCNature 487:486-490 (2012)Mapped to99+
A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.Shapira S.D., Gat-Viks I., Shum B.O., Dricot A., de Grace M.M., Wu L., Gupta P.B., Hao T., Silver S.J.[...], Hacohen N.View abstractCategoriesInteractionSourceIntAct: P03495PubMedEurope PMCCell 139:1255-1267 (2009)Mapped to99+
X-ray structures of NS1 effector domain mutants.Xia S., Robertus J.D.View abstractCategoriesStructureSourcePDB: 3KWG, PDB: 3KWIPubMedEurope PMCArch Biochem Biophys 494:198-204 (2010)Mapped to1
Structure of NS1A effector domain from the influenza A/Udorn/72 virus.Xia S., Monzingo A.F., Robertus J.D.View abstractCategoriesStructureSourcePDB: 3EE8, PDB: 3EE9PubMedEurope PMCActa Crystallogr D Biol Crystallogr 65:11-17 (2009)Mapped to1
Structural basis for suppression of a host antiviral response by influenza A virus.Das K., Ma L.C., Xiao R., Radvansky B., Aramini J., Zhao L., Marklund J., Kuo R.L., Twu K.Y.[...], Montelione G.T.View abstractCategoriesStructureSourcePDB: 2RHKPubMedEurope PMCProc Natl Acad Sci U S A 105:13093-13098 (2008)Mapped to2