P01869 · IGH1M_MOUSE

  • Protein
    Ig gamma-1 chain C region, membrane-bound form
  • Gene
    Ighg1
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Cellular Componentexternal side of plasma membrane
Cellular Componentextracellular space
Cellular Componentimmunoglobulin complex, circulating
Molecular Functionantigen binding
Molecular Functionimmunoglobulin receptor binding
Biological Processantibacterial humoral response
Biological Processantibody-dependent cellular cytotoxicity
Biological ProcessB cell differentiation
Biological Processcomplement activation, classical pathway
Biological Processdefense response to bacterium
Biological Processhumoral immune response mediated by circulating immunoglobulin
Biological Processimmunoglobulin mediated immune response
Biological Processphagocytosis, engulfment
Biological Processphagocytosis, recognition
Biological Processpositive regulation of immune response
Biological Processpositive regulation of phagocytosis
Biological Processpositive regulation of type I hypersensitivity
Biological Processpositive regulation of type IIa hypersensitivity

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ig gamma-1 chain C region, membrane-bound form

Gene names

    • Name
      Ighg1
    • Synonyms
      Igh-4

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    P01869

Proteomes

Organism-specific databases

Subcellular Location

Features

Showing features for transmembrane, topological domain.

TypeIDPosition(s)Description
Transmembrane340-357Helical
Topological domain358-393Cytoplasmic

Keywords

PTM/Processing

Features

Showing features for chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00001535831-393Ig gamma-1 chain C region, membrane-bound form
Disulfide bond27↔82
Disulfide bond102Interchain (with a light chain)
Disulfide bond104Interchain (with a heavy chain)
Disulfide bond107Interchain (with a heavy chain)
Disulfide bond109Interchain (with a heavy chain)
Disulfide bond138↔198
Glycosylation174N-linked (GlcNAc...) asparagine
Disulfide bond244↔302

Keywords

Proteomic databases

PTM databases

Interaction

Miscellaneous

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-97CH1
Region98-110Hinge
Region111-217CH2
Region218-324CH3

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

P01869-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Name
    Membrane-bound
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Length
    393
  • Mass (Da)
    43,387
  • Last updated
    1991-08-01 v2
  • Checksum
    4CC88343B7A1CE27
AKTTPPSVYPLAPGSAAQTNSMVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSPRPSETVTCNVAHPASSTKVDKKIVPRDCGCKPCICTVPEVSSVFIFPPKPKDVLTITLTPKVTCVVVDISKDDPEVQFSWFVDDVEVHTAQTQPREEQFNSTFRSVSELPIMHQDWLNGKEFKCRVNSAAFPAPIEKTISKTKGRPKAPQVYTIPPPKEQMAKDKVSLTCMITDFFPEDITVEWQWNGQPAENYKNTQPIMNTNGSYFVYSKLNVQKSNWEAGNTFTCSVLHEGLHNHHTEKSLSHSPGLQLDETCAEAQDGELDGLWTTITIFISLFLLSVCYSAAVTLFKVKWIFSSVVELKQTLVPEYKNMIGQAP

P01868-1

The sequence of this isoform can be found in the external entry linked below. Isoforms of the same protein are often annotated in two different entries if their sequences differ significantly.

View isoform
  • Name
    Secreted
  • See also
    sequence in UniParc or sequence clusters in UniRef

Computationally mapped potential isoform sequences

There are 3 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A075B5P4A0A075B5P4_MOUSEIghg1324
A0A0A6YWR2A0A0A6YWR2_MOUSEIghg1393
P01868IGHG1_MOUSEIghg1324

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
J00453
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.

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Disclaimer

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