P00942 · TPIS_YEAST

Function

Miscellaneous

Present with 207000 molecules/cell in log phase SD medium.

Catalytic activity

Pathway

Carbohydrate biosynthesis; gluconeogenesis.
Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.

Features

Showing features for binding site, active site.

124820406080100120140160180200220240
TypeIDPosition(s)Description
Binding site10substrate
Binding site12substrate
Active site95Electrophile
Active site165Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentmitochondrion
Cellular Componentplasma membrane
Molecular Functiontriose-phosphate isomerase activity
Biological Processgluconeogenesis
Biological Processglyceraldehyde-3-phosphate biosynthetic process
Biological Processglycerol catabolic process
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Triosephosphate isomerase
  • EC number
  • Short names
    TIM
  • Alternative names
    • Triose-phosphate isomerase

Gene names

    • Name
      TPI1
    • ORF names
      YD9609.05C
    • Ordered locus names
      YDR050C

Organism names

Accessions

  • Primary accession
    P00942
  • Secondary accessions
    • D6VS37

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for initiator methionine, chain, modified residue, cross-link.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00000901692-248Triosephosphate isomerase
Modified residue4Phosphothreonine
Modified residue71Phosphoserine
Modified residue215Phosphoserine
Cross-link223Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)

Keywords

Proteomic databases

PTM databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Miscellaneous

Family & Domains

Sequence similarities

Belongs to the triosephosphate isomerase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    248
  • Mass (Da)
    26,795
  • Last updated
    2007-01-23 v2
  • Checksum
    8429251C4DF51F86
MARTFFVGGNFKLNGSKQSIKEIVERLNTASIPENVEVVICPPATYLDYSVSLVKKPQVTVGAQNAYLKASGAFTGENSVDQIKDVGAKWVILGHSERRSYFHEDDKFIADKTKFALGQGVGVILCIGETLEEKKAGKTLDVVERQLNAVLEEVKDWTNVVVAYEPVWAIGTGLAATPEDAQDIHASIRKFLASKLGDKAASELRILYGGSANGSNAVTFKDKADVDGFLVGGASLKPEFVDIINSRN

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
J01366
EMBL· GenBank· DDBJ
AAA88757.1
EMBL· GenBank· DDBJ
Genomic DNA
Z49209
EMBL· GenBank· DDBJ
CAA89080.1
EMBL· GenBank· DDBJ
Genomic DNA
AY557654
EMBL· GenBank· DDBJ
AAS55980.1
EMBL· GenBank· DDBJ
Genomic DNA
BK006938
EMBL· GenBank· DDBJ
DAA11897.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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