P00785 · ACTN_ACTCC

Function

function

Cysteine protease responsible for the cleavage of kiwellin into kissper and KiTH.

Catalytic activity

Activity regulation

Repressed by the active-site-directed cysteine protease inhibitor E64 (L-trans-epoxysuccinyl-leucylamide-(4-guanido)-butane) produced by Aspergillus japonicus.

Features

Showing features for active site, binding site.

138050100150200250300350
TypeIDPosition(s)Description
Active site151
Binding site151E64 (UniProtKB | ChEBI); inhibitor; produced by Aspergillus japonicus; covalent
Active site288
Active site308

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functioncysteine-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Actinidain
  • EC number
  • Short names
    Actinidin
  • Allergen name
    Act c 1

Gene names

    • Name
      ACT1A
    • ORF names
      CEY00_Acc12058

Organism names

Accessions

  • Primary accession
    P00785
  • Secondary accessions
    • A0A2R6QY08
    • A0A3G9DHM4
    • E5D7U1
    • E5D7U2
    • Q9AXD2

Proteomes

Genome annotation databases

Phenotypes & Variants

Allergenic properties

Causes an allergic reaction in human.

Keywords

Protein family/group databases

PTM/Processing

Features

Showing features for signal, propeptide, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-24
PropeptidePRO_000002639825-126Activation peptide
ChainPRO_0000026399127-380Actinidain
Disulfide bond148↔191
Disulfide bond182↔224
Disulfide bond282↔332

Keywords

Expression

Tissue specificity

Fruit.

Developmental stage

Levels of mRNA accumulate during early fruit development.

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the peptidase C1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    380
  • Mass (Da)
    42,098
  • Last updated
    2019-11-13 v5
  • Checksum
    C2DA505454525B93
MGLPKSFVSMSLLFFSTLLILSLAFNAKNLTQRTNDEVKAMYESWLIKYGKSYNSLGEWERRFEIFKETLRFIDEHNADTNRSYKVGLNQFADLTDEEFRSTYLGFTSGSNKTKVSNQYEPRVGQVLPSYVDWRSAGAVVDIKSQGECGGCWAFSAIATVEGINKIVTGVLISLSEQELIDCGRTQNTRGCNVGYITDGFQFIINNGGINTEENYPYTAQDGECNVDLQNEKYVTIDTYENVPYNNEWALQTAVTYQPVSVALDAAGDAFKHYSSGIFIGPCGTAIDHAVTIVGYGTEGGIDYWIVKNSWDTTWGEEGYMRILRNVGGAGTCGIATMPSYPVKYNNQNHPKSYSSLINPPAFSMSNDGPVGVDDGQRYSA

Sequence caution

The sequence CAA31435.1 differs from that shown. Reason: Frameshift
The sequence CAA31529.1 differs from that shown. Reason: Frameshift

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict27in Ref. 1; ADQ85985
Sequence conflict96in Ref. 5; CAA31435
Sequence conflict108in Ref. 5; CAA31435
Sequence conflict118in Ref. 1; ADQ85985/ADQ85986
Sequence conflict124in Ref. 5; CAA31435
Sequence conflict167-170in Ref. 6; AA sequence
Sequence conflict181in Ref. 5; CAA31435
Sequence conflict184in Ref. 5; CAA31435
Sequence conflict192in Ref. 6; AA sequence
Sequence conflict193in Ref. 1; ADQ85985
Sequence conflict193-194in Ref. 1; ADQ85986
Sequence conflict201in Ref. 1; ADQ85986
Sequence conflict206in Ref. 6; AA sequence
Sequence conflict212in Ref. 5; CAA31435
Sequence conflict223in Ref. 6; AA sequence
Sequence conflict225in Ref. 6; AA sequence
Sequence conflict226in Ref. 5; CAA31435
Sequence conflict227in Ref. 6; AA sequence
Sequence conflict230-231in Ref. 6; AA sequence
Sequence conflict240in Ref. 5; CAA31435
Sequence conflict272in Ref. 1; ADQ85985/ADQ85986
Sequence conflict274in Ref. 6; AA sequence
Sequence conflict279in Ref. 1; ADQ85985/ADQ85986
Sequence conflict290-291in Ref. 6; AA sequence
Sequence conflict301in Ref. 6; AA sequence
Sequence conflict307in Ref. 5; CAA31435
Sequence conflict349in Ref. 5; CAA31435/CAA31529
Sequence conflict360in Ref. 5; CAA31435/CAA31529
Sequence conflict366in Ref. 1; ADQ85985
Sequence conflict373in Ref. 5; CAA31435/CAA31529
Sequence conflict374in Ref. 5; CAA31529

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GU201520
EMBL· GenBank· DDBJ
ADQ85985.1
EMBL· GenBank· DDBJ
Genomic DNA
GU201528
EMBL· GenBank· DDBJ
ADQ85986.1
EMBL· GenBank· DDBJ
mRNA
LC330913
EMBL· GenBank· DDBJ
BBA83994.1
EMBL· GenBank· DDBJ
Genomic DNA
AF343446
EMBL· GenBank· DDBJ
AAK06862.1
EMBL· GenBank· DDBJ
mRNA
NKQK01000011
EMBL· GenBank· DDBJ
PSS17271.1
EMBL· GenBank· DDBJ
Genomic DNA
X13013
EMBL· GenBank· DDBJ
CAA31435.1
EMBL· GenBank· DDBJ
mRNA Frameshift
X13139
EMBL· GenBank· DDBJ
CAA31529.1
EMBL· GenBank· DDBJ
mRNA Frameshift

Genome annotation databases

Similar Proteins

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