O97961 · KTN1_VULVU

Function

function

Receptor for kinesin thus involved in kinesin-driven vesicle motility.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum membrane
Molecular Functionkinesin binding
Biological Processmicrotubule-based movement
Biological Processprotein transport

Names & Taxonomy

Protein names

  • Recommended name
    Kinectin

Gene names

    • Name
      KTN1

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Carnivora > Caniformia > Canidae > Vulpes

Accessions

  • Primary accession
    O97961

Proteomes

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass type II membrane protein
Note: Vesicle membrane protein anchored to the endoplasmic reticulum. In testis, localized at sperm surface.

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-6Cytoplasmic
Transmembrane7-29Helical; Signal-anchor for type II membrane protein
Topological domain30-1330Lumenal

Keywords

PTM/Processing

Features

Showing features for chain, modified residue, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00000843381-1330Kinectin
Modified residue75Phosphoserine
Modified residue77Phosphoserine
Modified residue153Phosphothreonine
Modified residue156Phosphoserine
Glycosylation172N-linked (GlcNAc...) asparagine
Glycosylation435N-linked (GlcNAc...) asparagine
Glycosylation772N-linked (GlcNAc...) asparagine
Glycosylation904N-linked (GlcNAc...) asparagine
Glycosylation1055N-linked (GlcNAc...) asparagine
Modified residue1085Phosphoserine
Glycosylation1236N-linked (GlcNAc...) asparagine
Modified residue1286Phosphoserine
Glycosylation1302N-linked (GlcNAc...) asparagine

Keywords

PTM databases

Expression

Tissue specificity

Expressed in male brain, heart, kidney, liver, lung, spleen and testis.

Interaction

Subunit

Parallel homodimers formed between the membrane-bound and the cytosolic form, and also between 2 cytosolic forms.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, coiled coil.

TypeIDPosition(s)Description
Region49-81Disordered
Compositional bias63-81Basic and acidic residues
Region108-218Disordered
Compositional bias120-139Basic and acidic residues
Compositional bias162-186Basic and acidic residues
Compositional bias203-218Basic and acidic residues
Coiled coil332-1329

Sequence similarities

Belongs to the kinectin family.

Keywords

Family and domain databases

Sequence & Isoforms

Align isoforms (3)
  • Sequence status
    Complete

This entry describes 3 isoforms produced by Alternative splicing. Additional isoforms seem to exist.

O97961-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    1,330
  • Mass (Da)
    153,478
  • Last updated
    1999-05-01 v1
  • Checksum
    CDCDD415B274F42B
MEFYESTYFIVLIPSVVITVIFLFFWLFMKETLYDEVLAKQKREQKLIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDEQVVPIPLNVVETSSSVRERKKKEKKHKPVLEEQVTKESDVSKIPGKKVEPVPVTKQPTPPSEAAASKKKPGQKKSKNGSDDQDKKVETLMAPSKKQESLPLQQETKQESGSGKKKVSSKKQKAENVLVDEPLIHATTYIPLMDNADSNPVLDKREVIDLIKPDQVEGIQKTGAKKLKTETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIQDALKRSSKGELTALVHQLQEKDKLLAAVKEDAAVMKDRCKQLTQEMMSEKERSNVVIARMKDRIGTLEKEHNVFQNKMHVSYQETQQMQMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQDYARLVNELTEKTGKLQQEEVQKKNAEQAVTQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDLQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVTKEESLQMQVQDILEQNEALKALIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLANEHDHLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQKSIHVKDDQIRLLEEQLQCEISNKMEEFKILNDQNKALQLEVQKLQILVSEQPNKDVVEQMEKCIQEKDEKLKTVEELLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAEVLKVANKEKTIQDLKQEIEALKEEIGNIQLEKAQQLSITSQIQELQNLLKGKEEQMNTMKTVLEEKEKDLASRGKWLQDLQEENESLKTHIQEVAQHNLKEACSASRLEELETVLKEKENEMKRIETILKERENDLSSKIKLLQEVQDENKLFKSEIEQLKQCNYQQASSFPPHEELLKVISEREKEITGLQNELDSLKEAVEHQRKKNNDLREKNWEAMEALASTEKMLQDKVNKTSKVERQQYVEAIELEAKEVLKKLFPKVSVPPNLNYGEWLRGFEKKPKECVAETSGSEEVKVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESQKTIKQMQLSFTSSEQELERLRRENKDIENLRREREHLEMELEKAEIERSTYVTEVRELKTQLNETLTKLRTEQSERQKVAGDLHKAQQSLDLIQSKIVKAAGDTTVIENSDVSPEAESSEKETMSVSLNQTVTQLQQLLQAVNQQLTKEKEHYQVLE

O97961-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

O97961-3

  • Name
    3
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Computationally mapped potential isoform sequences

There are 8 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A3Q7T7G2A0A3Q7T7G2_VULVUKTN11491
A0A3Q7T7G3A0A3Q7T7G3_VULVUKTN11460
A0A3Q7S9N6A0A3Q7S9N6_VULVUKTN11490
A0A3Q7SJ65A0A3Q7SJ65_VULVUKTN11357
A0A3Q7TMS6A0A3Q7TMS6_VULVUKTN11519
A0A3Q7TMU2A0A3Q7TMU2_VULVUKTN11468
A0A3Q7SLQ9A0A3Q7SLQ9_VULVUKTN11496
A0A3Q7SLR4A0A3Q7SLR4_VULVUKTN11462

Features

Showing features for compositional bias, alternative sequence.

TypeIDPosition(s)Description
Compositional bias63-81Basic and acidic residues
Compositional bias120-139Basic and acidic residues
Compositional bias162-186Basic and acidic residues
Compositional bias203-218Basic and acidic residues
Alternative sequenceVSP_007983834-856in isoform 2
Alternative sequenceVSP_0079841031-1060in isoform 3

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF095786
EMBL· GenBank· DDBJ
AAC64407.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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