A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing.Wilmes G.M., Bergkessel M., Bandyopadhyay S., Shales M., Braberg H., Cagney G., Collins S.R., Whitworth G.B., Kress T.L.[...], Krogan N.J.View abstractCited forINTERACTION WITH CSN12 AND THP3CategoriesInteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell 32:735-746 (2008)Cited in3Mapped to4
Sem1 is a functional component of the nuclear pore complex-associated messenger RNA export machinery.Faza M.B., Kemmler S., Jimeno S., Gonzalez-Aguilera C., Aguilera A., Hurt E., Panse V.G.View abstractCited forDISRUPTION PHENOTYPE, FUNCTION, SUBUNIT, INTERACTION WITH CSN12 AND THP3CategoriesFunction, Interaction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Cell Biol. 184:833-846 (2009)Cited in3Mapped to2
The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression.Schneider M., Hellerschmied D., Schubert T., Amlacher S., Vinayachandran V., Reja R., Pugh B.F., Clausen T., Kohler A.View abstractAnnotationPrimary LiteratureCategoriesStructure, Function, InteractionSourcePDB: 4TRQ, SGD: S000007235PubMedEurope PMCCell 162:1016-1028 (2015)Mapped to34
Structural characterization of the interaction of Ubp6 with the 26S proteasome.Aufderheide A., Beck F., Stengel F., Hartwig M., Schweitzer A., Pfeifer G., Goldberg A.L., Sakata E., Baumeister W., Forster F.View abstractAnnotationPrimary LiteratureCategoriesStructure, Function, InteractionSourcePDB: 5A5B, SGD: S000007235PubMedEurope PMCProc Natl Acad Sci U S A 112:8626-8631 (2015)Mapped to35
The intrinsically disordered Sem1 protein functions as a molecular tether during proteasome lid biogenesis.Tomko R.J. Jr., Hochstrasser M.View abstractAnnotationSem1 has a distinct chaperone-like function specific to early stages of proteasome assembly., Primary LiteratureCategoriesFunction, InteractionSourceGeneRif: 851967, SGD: S000007235PubMedEurope PMCMol Cell 53:433-443 (2014)Mapped to3
The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain.Pick E., Golan A., Zimbler J.Z., Guo L., Sharaby Y., Tsuge T., Hofmann K., Wei N.View abstractAnnotationS000007235CategoriesInteractionSourceSGD: S000007235PubMedEurope PMCPLoS One 7:e43980-e43980 (2012)Mapped to16
Structural basis for the assembly and nucleic acid binding of the TREX-2 transcription-export complex.Ellisdon A.M., Dimitrova L., Hurt E., Stewart M.View abstractAnnotationS000007235CategoriesStructure, Interaction, StructureSourcePDB: 3T5V, SGD: S000007235PubMedEurope PMCNat Struct Mol Biol 19:328-336 (2012)Mapped to8
Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes.Lee K.K., Sardiu M.E., Swanson S.K., Gilmore J.M., Torok M., Grant P.A., Florens L., Workman J.L., Washburn M.P.View abstractCategoriesInteractionSourceIntAct: O94742PubMedEurope PMCMol Syst Biol 7:503-503 (2011)Mapped to99+
Designed proteins to modulate cellular networks.Cortajarena A.L., Liu T.Y., Hochstrasser M., Regan L.View abstractAnnotationGenetic Interactions|Strains/Constructs|Other Features|Mutants/Phenotypes|Techniques and Reagents|Non-Fungal Related Genes/Proteins|Primary LiteratureCategoriesInteractionSourceSGD: S000007235PubMedEurope PMCACS Chem Biol 5:545-552 (2010)Mapped to1
PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika.Pick E., Hofmann K., Glickman M.H.View abstractAnnotationReviewsCategoriesInteractionSourceSGD: S000007235PubMedEurope PMCMol Cell 35:260-264 (2009)Mapped to18
An atlas of chaperone-protein interactions in Saccharomyces cerevisiae: implications to protein folding pathways in the cell.Gong Y., Kakihara Y., Krogan N., Greenblatt J., Emili A., Zhang Z., Houry W.A.View abstractCategoriesInteractionSourceIntAct: O94742PubMedEurope PMCMol Syst Biol 5:275-275 (2009)Mapped to99+
Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle.Saeki Y., Toh-E A., Kudo T., Kawamura H., Tanaka K.View abstractCategoriesInteractionSourceIntAct: O94742PubMedEurope PMCCell 137:900-913 (2009)Cited in1Mapped to24
Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle base.Funakoshi M., Tomko R.J. Jr., Kobayashi H., Hochstrasser M.View abstractCategoriesInteractionSourceIntAct: O94742PubMedEurope PMCCell 137:887-899 (2009)Cited in4Mapped to19
Hsm3/S5b participates in the assembly pathway of the 19S regulatory particle of the proteasome.Le Tallec B., Barrault M.B., Guerois R., Carre T., Peyroche A.View abstractAnnotationGenetic Interactions|Strains/Constructs|Protein-protein Interactions|Mutants/Phenotypes|Primary LiteratureCategoriesInteractionSourceSGD: S000007235PubMedEurope PMCMol. Cell 33:389-399 (2009)Cited in2Mapped to3
High-quality binary protein interaction map of the yeast interactome network.Yu H., Braun P., Yildirim M.A., Lemmens I., Venkatesan K., Sahalie J., Hirozane-Kishikawa T., Gebreab F., Li N.[...], Vidal M.View abstractCategoriesInteractionSourceIntAct: O94742PubMedEurope PMCScience 322:104-110 (2008)Mapped to99+
An in vivo map of the yeast protein interactome.Tarassov K., Messier V., Landry C.R., Radinovic S., Serna Molina M.M., Shames I., Malitskaya Y., Vogel J., Bussey H., Michnick S.W.View abstractCategoriesInteractionSourceIntAct: O94742PubMedEurope PMCScience 320:1465-1470 (2008)Mapped to99+
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.Krogan N.J., Cagney G., Yu H., Zhong G., Guo X., Ignatchenko A., Li J., Pu S., Datta N.[...], Greenblatt J.F.View abstractCategoriesInteractionSourceIntAct: O94742PubMedEurope PMCNature 440:637-643 (2006)Cited in1Mapped to99+
An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network.Guerrero C., Tagwerker C., Kaiser P., Huang L.View abstractAnnotationProtein-protein Interactions|Primary LiteratureCategoriesInteractionSourceIntAct: O94742, SGD: S000007235PubMedEurope PMCMol. Cell. Proteomics 5:366-378 (2006)Cited in2Mapped to94
Sem1, the yeast ortholog of a human BRCA2-binding protein, is a component of the proteasome regulatory particle that enhances proteasome stability.Funakoshi M., Li X., Velichutina I., Hochstrasser M., Kobayashi H.View abstractAnnotationGenetic Interactions|Protein-protein Interactions|Mutants/Phenotypes|Non-Fungal Related Genes/Proteins|Primary Literature|Function/ProcessCategoriesInteraction, Function, Interaction, Subcellular LocationSourceIntAct: O94742, SGD: S000007235PubMedEurope PMCJ Cell Sci 117:6447-6454 (2004)Mapped to11
Interaction between the product of the breast cancer susceptibility gene BRCA2 and DSS1, a protein functionally conserved from yeast to mammals.Marston N.J., Richards W.J., Hughes D., Bertwistle D., Marshall C.J., Ashworth A.View abstractAnnotationStrains/Constructs|Mutants/Phenotypes|Primary Literature|Function/ProcessCategoriesInteractionSourceSGD: S000007235PubMedEurope PMCMol. Cell. Biol. 19:4633-4642 (1999)Cited in2Mapped to2