O94489 · EF3_SCHPO

Function

function

Ribosome-dependent ATPase that functions in cytoplasmic translation elongation (PubMed:29300771).
Required for the ATP-dependent release of deacylated tRNA from the ribosomal E-site during protein biosynthesis (By similarity).
Stimulates the eEF1A-dependent binding of aminoacyl-tRNA to the ribosomal A-site, which has reduced affinity for tRNA as long as the E-site is occupied (By similarity).

Catalytic activity

Pathway

Protein biosynthesis; polypeptide chain elongation.

Features

Showing features for binding site.

110471002003004005006007008009001,000
TypeIDPosition(s)Description
Binding site467-474ATP 1 (UniProtKB | ChEBI)
Binding site707-714ATP 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionRNA binding
Molecular Functiontranslation elongation factor activity
Biological Processcytoplasmic translation
Biological Processcytoplasmic translational elongation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Elongation factor 3
  • EC number
  • Short names
    EF-3

Gene names

    • Name
      tef3
    • Synonyms
      ef3
    • ORF names
      SPCC417.08

Organism names

Accessions

  • Primary accession
    O94489
  • Secondary accessions
    • P78876
    • Q10266
    • Q9UUL5

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00000934571-1047Elongation factor 3
Modified residue714Phosphoserine
Modified residue768Phosphoserine
Modified residue783Phosphoserine
Modified residue1043Phosphoserine

Keywords

Proteomic databases

PTM databases

Interaction

Subunit

Monomer.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for repeat, domain, region.

Type
IDPosition(s)Description
Repeat48-85HEAT 1
Repeat91-128HEAT 2
Repeat130-167HEAT 3
Repeat171-208HEAT 4
Repeat210-246HEAT 5
Repeat247-284HEAT 6
Domain411-647ABC transporter 1
Domain673-1000ABC transporter 2
Region1022-1047Disordered

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,047
  • Mass (Da)
    115,802
  • Last updated
    1999-05-01 v1
  • Checksum
    10F5F10DB2E867F1
MSAKSENKQSVKALEELLKHLTVCDAAEEADAAKALASFVNGPIEEQDAPSQVFSAISKQLNDKNATARERVLKGLEAVANHGSVAADVEPYLVELLPAVIAKVADKQNAVRDAAIAASKAIVRCTTPYAVKAIVPSVLESIHTTGKWNEKMNSLQLLDVLVEVAPSQLSYSLPQIIPVVSESMWDTKAEVKKQSKETMTKVCTLIANADIDRFIPELINCIAHPEEVPETIHSLGATTFVTEVQAPTLSIMVPLLARGLNERSTPIKRKTAVIIDNMSKLVEDPQVVAPFLPKLLPGLYHIKDTIGDPECRSVVQRAITTLERVGNVVDGKIPEVSTAANPEVCLETLKAVLGEIKVPTNEEVIAKYVANIAAQLVEEKDNENESWVLNITPYLTAFIDEAHIHKIVEQLRTRSIAKIPGGASHAEEEEEGEDLCNCEFSLAYGAKILLNRTRLRLKRGRRYGLCGPNGSGKSTLMRAIVNGQVEGFPTHLRTVYVEHDIDESEADTPSVDFILQDPAVPIKDRDEIVKALKENSFTDELINMPIGSLSGGWKMKLALTRAMFKNPDILLLDEPTNHLDVVNVAWLENFLVNQKDVSSIIVSHDSGFLDHVVQAIIHYERFKLRKYLGNMSEFVKKVPSAKSYYELGASEMEFKFPEPGFLEGVKTKQRAIIKVQHMSFQYPGTSKPQLNDISFQVSLSSRIAVIGPNGAGKSTLIKVLTGELLPTVGEIYQHENCRIAYVAQAAFTHLGHHPDKTPSEYIQWRFQSGEDLEAMDKASRVISEADEEAMKNKIFKIEGTQRKILGIHSRRKLKNSYEYECSFLVGENIGMKSERWVPMMSSDNAWLPRGELMETHAKMVAEVDRAEALKSGQFRPLVRKEIEEHCSLLGLDAELVSHSRIKGLSGGQKVKLVLAACTWLRPHVIVLDEPTNYLDRDSLGALSKGLKNFGGGVVLVTHSREFTEGLTEEVWAVNNGHMTPSGHNWVSGQGSGPRIQEKEEGDTFDAFGNKIEKAKKAKKLTGAELRKKKKERMARRKAGLEVSDDEL

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict770-771in Ref. 3; BAA11573
Sequence conflict777in Ref. 3; BAA11573
Sequence conflict800-802in Ref. 3; BAA11573
Sequence conflict950in Ref. 3; BAA11573
Sequence conflict959in Ref. 4; BAA33896
Sequence conflict962in Ref. 2; BAA13887
Sequence conflict972in Ref. 2; BAA13887
Sequence conflict977in Ref. 2; BAA13887
Sequence conflict982in Ref. 2; BAA13887
Sequence conflict988in Ref. 2; BAA13887
Sequence conflict1001-1002in Ref. 2; BAA13887
Sequence conflict1009-1014in Ref. 2; BAA13887
Sequence conflict1023in Ref. 2; BAA13887

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CU329672
EMBL· GenBank· DDBJ
CAA22654.1
EMBL· GenBank· DDBJ
Genomic DNA
D89226
EMBL· GenBank· DDBJ
BAA13887.1
EMBL· GenBank· DDBJ
mRNA
D82575
EMBL· GenBank· DDBJ
BAA11573.1
EMBL· GenBank· DDBJ
mRNA
AB018538
EMBL· GenBank· DDBJ
BAA33896.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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