O94178 · SODC_COLGL

Function

function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Cu cation (UniProtKB | Rhea| CHEBI:23378 )

Note: Binds 1 copper ion per subunit.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site47Cu cation (UniProtKB | ChEBI); catalytic
Binding site49Cu cation (UniProtKB | ChEBI); catalytic
Binding site64Cu cation (UniProtKB | ChEBI); catalytic
Binding site64Zn2+ (UniProtKB | ChEBI); structural
Binding site72Zn2+ (UniProtKB | ChEBI); structural
Binding site81Zn2+ (UniProtKB | ChEBI); structural
Binding site84Zn2+ (UniProtKB | ChEBI); structural
Binding site121Cu cation (UniProtKB | ChEBI); catalytic
Binding site144substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functioncopper ion binding
Molecular Functionsuperoxide dismutase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Superoxide dismutase [Cu-Zn]
  • EC number

Gene names

    • Name
      SOD1

Organism names

Accessions

  • Primary accession
    O94178

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for initiator methionine, chain, disulfide bond.

TypeIDPosition(s)Description
Initiator methionine1Removed
ChainPRO_00001641152-154Superoxide dismutase [Cu-Zn]
Disulfide bond58↔147

Keywords

Interaction

Subunit

Homodimer.

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region124-144Disordered

Sequence similarities

Belongs to the Cu-Zn superoxide dismutase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    154
  • Mass (Da)
    15,966
  • Last updated
    2007-01-23 v3
  • Checksum
    177F4962166699AC
MVKAVCVVRGDSKVTGSIVFEQESESAPTKITWDISGNDANAKRGMHIHTFGDNTNGCTSAGPHFNPHNKTHGAPEDSNRHVGDLGNIETDANGNSKGTVTDSHVKLIGPESVIGRTIVVHGGTDDLGKGDNEESLKTGNAGPRPACGVIGISN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF076951
EMBL· GenBank· DDBJ
AAD19338.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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