O89252 · O89252_9FLAV
- ProteinGenome polyprotein
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids2842 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
Catalytic activity
- ATP + H2O = ADP + H+ + phosphate
Cofactor
Protein has several cofactor binding sites:
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGenome polyprotein
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Kitrinoviricota > Flasuviricetes > Amarillovirales > Flaviviridae > Pegivirus > Pegivirus hominis
Accessions
- Primary accessionO89252
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Endoplasmic reticulum membrane ; Peripheral membrane protein
Host endoplasmic reticulum membrane ; Multi-pass membrane protein
Host endoplasmic reticulum membrane ; Peripheral membrane protein
Membrane ; Multi-pass membrane protein
Membrane ; Peripheral membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 165-185 | Helical | ||||
Sequence: FWRGVMSLTPLLVCVAALLLL | ||||||
Transmembrane | 548-575 | Helical | ||||
Sequence: FVFVLLYLMKLAEARLVPLILLLLWWWV | ||||||
Transmembrane | 595-622 | Helical | ||||
Sequence: FAGPALSWCLGLPTVSMILGLANLVLYF | ||||||
Transmembrane | 634-653 | Helical | ||||
Sequence: VLWKLARGAFPLALLMGISA | ||||||
Transmembrane | 673-693 | Helical | ||||
Sequence: VDTSVLGWVVASVVAWAIAIL | ||||||
Transmembrane | 750-772 | Helical | ||||
Sequence: AVMMVVVALVLLFGLFDALDWAL | ||||||
Transmembrane | 1525-1548 | Helical | ||||
Sequence: ILMVGLAIAGGMIYASYTGSLVVV | ||||||
Transmembrane | 1709-1736 | Helical | ||||
Sequence: ALLLGAAGTALGTPVVGLTMAGAFMGGA | ||||||
Transmembrane | 1742-1764 | Helical | ||||
Sequence: LVTVLLGAVGGWEGVVNAASLVF | ||||||
Transmembrane | 1776-1800 | Helical | ||||
Sequence: LWYAIPVLTSPGAGLAGIALGLVLY |
Keywords
- Cellular component
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 769-894 | Peptidase C18 | ||||
Sequence: DWALEELLVSRPSLRRLARVVECCVMAGERATTVRLVSKMCARGAYLFDHMGSFSRAVKERLLEWDAALEPLSFTRTDCRIIRDAARTLSCGQCVMGLPVVARRGDEVLIGVFQDVNHLPPGFVPT | ||||||
Domain | 894-1074 | Peptidase S29 | ||||
Sequence: TAPVVIRRCGKGFLGVTKAALTGRDPDLHPGNVMVLGTATSRSMGTCLNGLLFTTFHGASSRTIATPVGALNPRWWSASDDVTVYPPPMGATSLTPATCQAESLLVIRSDGPLCHGLGKGDKVELDVAMEVADFRGSSGSPVLCDEGHAVGMLVSVLHSGGRVTAARFTRPWTQVPTDAKT | ||||||
Domain | 1081-1237 | Helicase ATP-binding | ||||
Sequence: VPAKGVFKEAPLFMPTGAGKSTRVPLEYGNMGHKVLILNPSVATVRAMGPYMERLAGKHPSIYCGHDTTAFTRITDSPLTYSTYGRFLANPRQMLRGVPVVICDECHSHDSTVLLGIGRVRELARGCGVQLVLYATATPPGSPMTQHPSIIETNLTL | ||||||
Region | 2144-2167 | Disordered | ||||
Sequence: VTESGSGEFTPSVSSSQEDTPSSD | ||||||
Domain | 2487-2601 | RdRp catalytic | ||||
Sequence: PCAICVDATCFDSSITEEDVALETELYALASDHPEWVRALGKYYASGTMVTPEGVPVGERYCRSSGVLTTSASNCLTCYIKVKAACDRVGLKNVSLLIAGDDCLIICERPMCDPS |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length2,842
- Mass (Da)307,204
- Last updated1998-11-01 v1
- Checksum1BDF7D4E58AFA911