O86262 · TPMT_PSESJ
- ProteinThiopurine S-methyltransferase
- Genetpm
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids218 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Involved in the biological cycling of tellurium and selenium. Tellurium resistance (Ter) mechanism.
Catalytic activity
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 10 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: W | ||||||
Binding site | 45 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: L | ||||||
Binding site | 66 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 123 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | ||||
Sequence: R |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | thiopurine S-methyltransferase activity | |
Biological Process | methylation | |
Biological Process | response to metal ion | |
Biological Process | response to tellurium ion |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameThiopurine S-methyltransferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas > Pseudomonas syringae
Accessions
- Primary accessionO86262
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000220129 | 1-218 | Thiopurine S-methyltransferase | |||
Sequence: MKADFWLQRWSAGQIGFHQSEVNKDLQQYWSSLNVVPGARVLVPLCGKSQDMSWLSGQGYHVVGAELSEAAVERYFTERGEQPHITSQGDFKVYAAPGIEIWCGDFFALTARDIGHCAAFYDRAAMIALPADMRERYVQHLEALMPQACSGLLITLEYDQALLEGPPFSVPQTWLHRVMSGNWEVTKVGGQDTLHSSARGLKAGLERMDEHVYVLERV |
Structure
Sequence
- Sequence statusComplete
- Length218
- Mass (Da)24,446
- Last updated1998-11-01 v1
- Checksum5CD188EA5F9D171F
Keywords
- Technical term