O84767 · MUDD_CHLTR

Function

function

Cell wall formation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: Binds 2 magnesium or manganese ions per subunit.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site111-117ATP (UniProtKB | ChEBI)
Binding site600-655ATP (UniProtKB | ChEBI)
Binding site732Mg2+ 1 (UniProtKB | ChEBI)
Binding site745Mg2+ 1 (UniProtKB | ChEBI)
Binding site745Mg2+ 2 (UniProtKB | ChEBI)
Binding site747Mg2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionD-alanine-D-alanine ligase activity
Molecular Functionmetal ion binding
Molecular FunctionUDP-N-acetylmuramate-L-alanine ligase activity
Biological Processcell division
Biological Processcell wall organization
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Bifunctional enzyme MurC/Ddl

Including 2 domains:

  • Recommended name
    UDP-N-acetylmuramate--L-alanine ligase
  • EC number
  • Alternative names
    • UDP-N-acetylmuramoyl-L-alanine synthetase
  • Recommended name
    D-alanine--D-alanine ligase
  • EC number
  • Alternative names
    • D-Ala-D-Ala ligase
    • D-alanylalanine synthetase

Gene names

    • Name
      murC/ddl
    • Ordered locus names
      CT_762

Organism names

Accessions

  • Primary accession
    O84767

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001779161-803Bifunctional enzyme MurC/Ddl

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region1-446UDP-N-acetylmuramate--alanine ligase
Region447-803D-alanine--D-alanine ligase
Domain567-778ATP-grasp

Sequence similarities

In the N-terminal section; belongs to the MurCDEF family.
In the C-terminal section; belongs to the D-alanine--D-alanine ligase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    803
  • Mass (Da)
    89,230
  • Last updated
    1998-11-01 v1
  • Checksum
    82BB523BF1F4C1C8
MMKSLFYHFIGIGGIGMSALAHVLLDRGYSVSGSDLSEGKVVEKLKNKGAEFFLGNQEEHIPEGAVVVYSSSISKKNPEFLSAKSRGNRVVHRAELLAELAQDQISIFVTGSHGKTTVSSLITAILQEAKKNPSFAIGGLNQEGINGGSGSEYFVAEADESDGSIRCYTPEFSVITNIDDEHLSNFEGDRELLLASLKDFALKTQQICWYNGDCPRLRSCLQGHTFGLDSSCDLHILSYYQEGWRLYFTAKYQDVVYADIEVQLVGMHNVLNAAAAMGIALSLGIDEGAIRNAFRGFSGVQRRLQRKNSSETFLFLEDYAHHPSEISCTLRAVRTAVGQRRILAIYQPHRFSRLRECIDSFPSAFKDADEVLLTEVYSAGEEAEDISYQKLAEAISQESIVKCTHIPFHELQRHLEQSIRVHDVCVSLGAGNIVNLGEKLRDFEPQKLHLGIICGGKSCEHEISVLSAKNIAKHLSKSFYDVSYFLITREGLWESVSSLETAEDSGKSVFDPEIAQRLEKVDVVLPILHGPYGEDGAMQGFLETIGKPYTGPAIAFSAIAMNKVFTKRFMSDLGIPVVPYLPLTLAGWKQEQDKWLAHIVEAFSFPIFVKSSHLGSSIGVFEVHNVIELRDAINEAFMRDNDVFVEENRLGCKEIEVSVLGDGSGAFVVAGLHERRGSGGFIDYQEKYGLSGKSSAQIVFDTDLSKEIQEQILEAADKIYRLLLGKGSCRIDFFVDEEGNFWLSEMNPIPGMTETSPFLTSFIRKGWSYEQIVHQLVIDGLQRFNQRQRLISTSFVDQAFAIQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE001273
EMBL· GenBank· DDBJ
AAC68357.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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