O84378 · AAXB_CHLTR
- ProteinPyruvoyl-dependent arginine decarboxylase AaxB
- GeneaaxB
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids195 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity).
Catalytic activity
- L-arginine + H+ = agmatine + CO2
Cofactor
Note: Binds 1 pyruvoyl group covalently per subunit.
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 52-53 | Cleavage (non-hydrolytic) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | arginine decarboxylase activity | |
Biological Process | arginine catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePyruvoyl-dependent arginine decarboxylase AaxB
- EC number
- Short namesPvlArgDC
- Alternative names
- Cleaved into 2 chains
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Chlamydiota > Chlamydiia > Chlamydiales > Chlamydiaceae > Chlamydia/Chlamydophila group > Chlamydia
Accessions
- Primary accessionO84378
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000364047 | 1-52 | Pyruvoyl-dependent arginine decarboxylase subunit beta | ||
Modified residue | 53 | Pyruvic acid (Ser) | |||
Chain | PRO_0000364048 | 53-195 | Pyruvoyl-dependent arginine decarboxylase subunit alpha | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length195
- Mass (Da)21,864
- Last updated1998-11-01 v1
- Checksum2BF6DCA22A2F705A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE001273 EMBL· GenBank· DDBJ | AAC67969.1 EMBL· GenBank· DDBJ | Genomic DNA |