O84378 · AAXB_CHLTR

Function

function

Part of the AaxABC system, catalyzes the decarboxylation of L-arginine. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (By similarity).

Catalytic activity

Cofactor

pyruvate (UniProtKB | Rhea| CHEBI:15361 )

Note: Binds 1 pyruvoyl group covalently per subunit.

Features

Showing features for site.

119520406080100120140160180
TypeIDPosition(s)Description
Site52-53Cleavage (non-hydrolytic)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionarginine decarboxylase activity
Biological Processarginine catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      aaxB
    • Ordered locus names
      CT_373

Organism names

Accessions

  • Primary accession
    O84378

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00003640471-52Pyruvoyl-dependent arginine decarboxylase subunit beta
Modified residue53Pyruvic acid (Ser)
ChainPRO_000036404853-195Pyruvoyl-dependent arginine decarboxylase subunit alpha

Interaction

Subunit

Trimer of an alpha-beta dimer.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    195
  • Mass (Da)
    21,864
  • Last updated
    1998-11-01 v1
  • Checksum
    2BF6DCA22A2F705A
MPYGTRYPTLAFHTGGVGESDDGMPPQPFETFCYDSALLQAKIENFNIVPYTSVLPKELFGNILPVDQCTKFFKHGAVLEVIMAGRGATVTDGTQAIATGVGICWGKDKNGELIRGWAAEYVEFFPTWIDDEIAESHAKMWLKKSLQHELDLRSISKHSEFQYFHNYINIRKKFGFCLTALGFLNFENAAPAVIQ

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE001273
EMBL· GenBank· DDBJ
AAC67969.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help