O82204 · RL281_ARATH
- ProteinLarge ribosomal subunit protein eL28z
- GeneRPL28A
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids143 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Component of the large ribosomal subunit (By similarity).
Essential in leaf polarity establishment, probably having a role for translation in leaf dorsoventral patterning to specify leaf adaxial identity (PubMed:18305007).
Essential in leaf polarity establishment, probably having a role for translation in leaf dorsoventral patterning to specify leaf adaxial identity (PubMed:18305007).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Cellular Component | cytoplasm | |
Cellular Component | cytosolic large ribosomal subunit | |
Cellular Component | cytosolic ribosome | |
Cellular Component | mitochondrion | |
Cellular Component | nucleolus | |
Cellular Component | nucleoplasm | |
Cellular Component | nucleus | |
Cellular Component | plant-type cell wall | |
Cellular Component | plasma membrane | |
Cellular Component | plasmodesma | |
Molecular Function | mRNA binding | |
Molecular Function | structural constituent of ribosome | |
Biological Process | adaxial/abaxial pattern specification | |
Biological Process | leaf morphogenesis | |
Biological Process | translation |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameLarge ribosomal subunit protein eL28z
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionO82204
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Pale green leaves and slightly longer early appearing leaves (PubMed:18305007).
Delayed leaf growth and abnormal leaf patterning, with the abaxial mesophyll features appearing in the adaxial mesophyll domain (PubMed:18305007).
More proximal vein branching in the petiole and reduced number of small veins at later leaf developmental stages (PubMed:18305007).
Abnormal inflorescences terminating early and producing several secondary inflorescences (PubMed:18305007).
Double mutant ae5-1 as2-101 exhibits an increased number of lotus- and needle-like leaves (PubMed:18305007).
The double mutant ae5 as1/2 produces severe abaxialized leaves (PubMed:18305007).
Delayed leaf growth and abnormal leaf patterning, with the abaxial mesophyll features appearing in the adaxial mesophyll domain (PubMed:18305007).
More proximal vein branching in the petiole and reduced number of small veins at later leaf developmental stages (PubMed:18305007).
Abnormal inflorescences terminating early and producing several secondary inflorescences (PubMed:18305007).
Double mutant ae5-1 as2-101 exhibits an increased number of lotus- and needle-like leaves (PubMed:18305007).
The double mutant ae5 as1/2 produces severe abaxialized leaves (PubMed:18305007).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 8 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000244743 | 1-143 | Large ribosomal subunit protein eL28z | |||
Sequence: MATVPGQLIWEIVKNNNCFLVKQFGRGNSKVQFSKETNNLTNVHSYKHSGLANKKTVTIQAADKDQAVVLATTKTKKQNKPKLSVNKSILKKEFPRMSKAVANQVVDNYYRPDLKKAALARLSAISKGLRVAKSGAKQRNRQA |
Proteomic databases
PTM databases
Expression
Tissue specificity
Expressed in seedlings, roots, stems, leaves, inflorescences and siliques.
Developmental stage
Detected in the embryo and leaf primordia at earlier developmental stages (PubMed:18305007).
In reproductive organs, expressed in the inflorescence meristem, floral primordia and four types of young floral organs (PubMed:18305007).
In reproductive organs, expressed in the inflorescence meristem, floral primordia and four types of young floral organs (PubMed:18305007).
Gene expression databases
Structure
Sequence
- Sequence statusComplete
- Length143
- Mass (Da)15,895
- Last updated1998-11-01 v1
- ChecksumBD1FBFFED28E5550
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC005169 EMBL· GenBank· DDBJ | AAC62149.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC06918.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC06919.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002685 EMBL· GenBank· DDBJ | AEC06920.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY050769 EMBL· GenBank· DDBJ | AAK92704.1 EMBL· GenBank· DDBJ | mRNA | ||
AY079378 EMBL· GenBank· DDBJ | AAL85109.1 EMBL· GenBank· DDBJ | mRNA |