O82204 · RL281_ARATH

Function

function

Component of the large ribosomal subunit (By similarity).
Essential in leaf polarity establishment, probably having a role for translation in leaf dorsoventral patterning to specify leaf adaxial identity (PubMed:18305007).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast
Cellular Componentcytoplasm
Cellular Componentcytosolic large ribosomal subunit
Cellular Componentcytosolic ribosome
Cellular Componentmitochondrion
Cellular Componentnucleolus
Cellular Componentnucleoplasm
Cellular Componentnucleus
Cellular Componentplant-type cell wall
Cellular Componentplasma membrane
Cellular Componentplasmodesma
Molecular FunctionmRNA binding
Molecular Functionstructural constituent of ribosome
Biological Processadaxial/abaxial pattern specification
Biological Processleaf morphogenesis
Biological Processtranslation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Large ribosomal subunit protein eL28z
  • Alternative names
    • 60S ribosomal protein L28-1
    • Protein ASYMMETRIC LEAVES1/2 ENHANCER 5

Gene names

    • Name
      RPL28A
    • Synonyms
      AE5
    • ORF names
      F6F22.24
    • Ordered locus names
      At2g19730

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    O82204

Proteomes

Organism-specific databases

Genome annotation databases

Phenotypes & Variants

Disruption phenotype

Pale green leaves and slightly longer early appearing leaves (PubMed:18305007).
Delayed leaf growth and abnormal leaf patterning, with the abaxial mesophyll features appearing in the adaxial mesophyll domain (PubMed:18305007).
More proximal vein branching in the petiole and reduced number of small veins at later leaf developmental stages (PubMed:18305007).
Abnormal inflorescences terminating early and producing several secondary inflorescences (PubMed:18305007).
Double mutant ae5-1 as2-101 exhibits an increased number of lotus- and needle-like leaves (PubMed:18305007).
The double mutant ae5 as1/2 produces severe abaxialized leaves (PubMed:18305007).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 8 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002447431-143Large ribosomal subunit protein eL28z

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in seedlings, roots, stems, leaves, inflorescences and siliques.

Developmental stage

Detected in the embryo and leaf primordia at earlier developmental stages (PubMed:18305007).
In reproductive organs, expressed in the inflorescence meristem, floral primordia and four types of young floral organs (PubMed:18305007).

Gene expression databases

Interaction

Subunit

Component of the large ribosomal subunit.

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    143
  • Mass (Da)
    15,895
  • Last updated
    1998-11-01 v1
  • Checksum
    BD1FBFFED28E5550
MATVPGQLIWEIVKNNNCFLVKQFGRGNSKVQFSKETNNLTNVHSYKHSGLANKKTVTIQAADKDQAVVLATTKTKKQNKPKLSVNKSILKKEFPRMSKAVANQVVDNYYRPDLKKAALARLSAISKGLRVAKSGAKQRNRQA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC005169
EMBL· GenBank· DDBJ
AAC62149.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06918.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06919.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC06920.1
EMBL· GenBank· DDBJ
Genomic DNA
AY050769
EMBL· GenBank· DDBJ
AAK92704.1
EMBL· GenBank· DDBJ
mRNA
AY079378
EMBL· GenBank· DDBJ
AAL85109.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp