O80501 · RAH1B_ARATH

Function

function

Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Binds GTP and GDP and possesses intrinsic GTPase activity (By similarity).

Features

Showing features for binding site.

120820406080100120140160180200
TypeIDPosition(s)Description
Binding site16-23GTP (UniProtKB | ChEBI)
Binding site64-68GTP (UniProtKB | ChEBI)
Binding site122-125GTP (UniProtKB | ChEBI)
Binding site152-153GTP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular Componentendosome
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi membrane
Cellular Componentmembrane
Cellular Componentplant-type vacuole
Cellular Componentplasma membrane
Cellular Componentplasmodesma
Cellular Componenttrans-Golgi network
Molecular FunctionGTP binding
Molecular FunctionGTPase activity
Biological Processexocytosis
Biological Processplant-type cell wall cellulose biosynthetic process
Biological Processprotein transport
Biological Processregulation of cell growth

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Ras-related protein RABH1b
  • Short names
    AtRABH1b
  • Alternative names
    • Ras-related protein Rab6A (AtRab6A)

Gene names

    • Name
      RABH1B
    • Synonyms
      RAB6A
    • ORF names
      F16B22.10
    • Ordered locus names
      At2g44610

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    O80501

Proteomes

Organism-specific databases

Genome annotation databases

Phenotypes & Variants

Features

Showing features for mutagenesis.

TypeIDPosition(s)Description
Mutagenesis23Loss of GTP-binding activity. No effect on targeting to Golgi.
Mutagenesis68No effect on GTP-binding activity and targeting to Golgi.
Mutagenesis122Loss of GTP-binding activity and targeting to Golgi. Loss of GTP-binding activity; when associated with 206-C--C-208 Del.
Mutagenesis206Loss of targeting to Golgi; when associated with S-208.
Mutagenesis206-208No effect on GTP-binding activity. Loss of GTP-binding activity; when associated with I-122.
Mutagenesis208Loss of targeting to Golgi; when associated with S-206.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 3 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain, lipidation, modified residue.

TypeIDPosition(s)Description
ChainPRO_00003485421-208
Lipidation206S-geranylgeranyl cysteine
Modified residue208Cysteine methyl ester
Lipidation208S-geranylgeranyl cysteine

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in roots, stems, leaves and flowers.

Gene expression databases

Interaction

Subunit

Interacts with the C-terminus of GC5, but not with GC3.

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for motif.

TypeIDPosition(s)Description
Motif38-46Effector region

Sequence similarities

Belongs to the small GTPase superfamily. Rab family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    208
  • Mass (Da)
    23,130
  • Last updated
    1998-11-01 v1
  • Checksum
    CD0EC2862AC7D0B7
MAPVSALAKYKLVFLGDQSVGKTSIITRFMYDKFDNTYQATIGIDFLSKTMYLEDRTVRLQLWDTAGQERFRSLIPSYIRDSSVAVIVYDVASRQSFLNTTKWIDEVRTERGSDVIVVLVGNKTDLVDKRQVSIEEAEAKARELNVMFIETSAKAGFNIKALFRKIAAALPGMETLSSTKQEDMVDVNLKSSNANASLAQQQSGGCSC

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC003672
EMBL· GenBank· DDBJ
AAC27463.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC10447.1
EMBL· GenBank· DDBJ
Genomic DNA
BT025780
EMBL· GenBank· DDBJ
ABF83670.1
EMBL· GenBank· DDBJ
mRNA
AK226988
EMBL· GenBank· DDBJ
BAE99055.1
EMBL· GenBank· DDBJ
mRNA
AY087904
EMBL· GenBank· DDBJ
AAM65455.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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