O80433 · CISY_DAUCA
- ProteinCitrate synthase, mitochondrial
- GeneCS
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids472 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Miscellaneous
Citrate synthase is found in nearly all cells capable of oxidative metabolism.
Catalytic activity
- oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H+
Pathway
Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.
Features
Showing features for active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 308 | ||||
Active site | 354 | ||||
Active site | 409 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrial matrix | |
Molecular Function | citrate (Si)-synthase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | citrate metabolic process | |
Biological Process | tricarboxylic acid cycle |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCitrate synthase, mitochondrial
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > campanulids > Apiales > Apiaceae > Apioideae > Scandiceae > Daucinae > Daucus > Daucus sect. Daucus
Accessions
- Primary accessionO80433
Subcellular Location
PTM/Processing
Features
Showing features for chain, transit peptide.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000005487 | ?-472 | Citrate synthase, mitochondrial | ||
Transit peptide | 1-? | Mitochondrion | |||
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length472
- Mass (Da)52,657
- Last updated1998-11-01 v1
- MD5 Checksum396E32511608A5EC200B78639AD14299
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB017159 EMBL· GenBank· DDBJ | BAA32557.1 EMBL· GenBank· DDBJ | mRNA |