O64437 · RINO1_ORYSJ

Function

function

Key enzyme in myo-inositol biosynthesis pathway that catalyzes the conversion of glucose 6-phosphate to 1-myo-inositol 1-phosphate in a NAD-dependent manner (By similarity).
Is a key enzyme in the phytic acid biosynthesis pathway in seeds (PubMed:19021878).

Miscellaneous

Plants silencing RINO1 show a low phytic acid phenotype in seeds, and high accumulation of inorganic phosphate (Pi) in seeds.

Catalytic activity

Cofactor

NAD+ (UniProtKB | Rhea| CHEBI:57540 )

Pathway

Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 1/2.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site70NAD+ (UniProtKB | ChEBI)
Binding site71NAD+ (UniProtKB | ChEBI)
Binding site72NAD+ (UniProtKB | ChEBI)
Binding site73NAD+ (UniProtKB | ChEBI)
Binding site143NAD+ (UniProtKB | ChEBI)
Binding site180NAD+ (UniProtKB | ChEBI)
Binding site190NAD+ (UniProtKB | ChEBI)
Binding site193NAD+ (UniProtKB | ChEBI)
Binding site230NAD+ (UniProtKB | ChEBI)
Binding site231NAD+ (UniProtKB | ChEBI)
Binding site232NAD+ (UniProtKB | ChEBI)
Binding site233NAD+ (UniProtKB | ChEBI)
Binding site281NAD+ (UniProtKB | ChEBI)
Binding site282NAD+ (UniProtKB | ChEBI)
Binding site306NAD+ (UniProtKB | ChEBI)
Binding site309NAD+ (UniProtKB | ChEBI)
Binding site340NAD+ (UniProtKB | ChEBI)
Binding site341NAD+ (UniProtKB | ChEBI)
Binding site342NAD+ (UniProtKB | ChEBI)
Binding site355NAD+ (UniProtKB | ChEBI)
Binding site393NAD+ (UniProtKB | ChEBI)
Binding site394NAD+ (UniProtKB | ChEBI)
Binding site422NAD+ (UniProtKB | ChEBI)
Binding site423NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentcytosol
Cellular Componentnucleus
Molecular Functioninositol-3-phosphate synthase activity
Biological Processinositol biosynthetic process
Biological Processphospholipid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Inositol-3-phosphate synthase 1
  • EC number
  • Short names
    MIP synthase 1
  • Alternative names
    • Myo-inositol 1-phosphate synthase
      (IPS
      ; MI-1-P synthase
      )
    • OsINO1-1

Gene names

    • Name
      RINO1
    • Synonyms
      INO1
      , INO1-1
    • Ordered locus names
      Os03g0192700
      , LOC_Os03g09250

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Kamenoo
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    O64437
  • Secondary accessions
    • Q10QK8

Proteomes

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
ChainPRO_00001951951-510UniProtInositol-3-phosphate synthase 1
Modified residue (large scale data)476PTMeXchangePhosphothreonine

Proteomic databases

Expression

Tissue specificity

Highly expressed in embryos, but transcripts are undetectable in roots, leaves, flowers and anthers.

Induction

Induced by sucrose and glucose (PubMed:11975732).
Induced by abscisic acid (ABA) (PubMed:11975732, PubMed:24467907).

Developmental stage

Expressed in the apical region of globular-stage embryos 2 days after anthesis (DAA). Expressed in the scutellum and aleurone layer 4 DAA. Expression in these cells increases until 7 DAA, and then gradually decreases.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    510
  • Mass (Da)
    56,264
  • Last updated
    2006-05-16 v2
  • Checksum
    20DD8DFAD199F937
MFIESFRVESPHVRYGAAEIESDYQYDTTELVHESHDGASRWIVRPKSVRYNFRTTTTVPKLGVMLVGWGGNNGSTLTAGVIANREGISWATKDKVQQANYYGSLTQASTIRVGSYNGEEIYAPFKSLLPMVNPDDLVFGGWDISNMNLADAMTRAKVLDIDLQKQLRPYMESMVPLPGIYDPDFIAANQGSRANNVIKGTKKEQMEQIIKDIREFKEKSKVDKVVVLWTANTERYSNVCVGLNDTMENLLASVDKNEAEISPSTLYAIACVMEGIPFINGSPQNTFVPGLIDLAIKNNCLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVSSNAILYELGEHPDHVVVIKYVPYVGDSKRAMDEYTSEIFMGGKSTIVLHNTCEDSLLAAPIILDLVLLAELSTRIQLKAEGEEKFHSFHPVATILSYLTKAPLVPPGTPVVNALAKQRAMLENIMRACVGLAPENNMILEYK

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict185in Ref. 1; BAA25729

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB012107
EMBL· GenBank· DDBJ
BAA25729.1
EMBL· GenBank· DDBJ
mRNA
EU267961
EMBL· GenBank· DDBJ
ACA50483.1
EMBL· GenBank· DDBJ
mRNA
AC116604
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
DP000009
EMBL· GenBank· DDBJ
ABF94419.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008209
EMBL· GenBank· DDBJ
BAF11156.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014959
EMBL· GenBank· DDBJ
BAS82735.1
EMBL· GenBank· DDBJ
Genomic DNA
CM000140
EMBL· GenBank· DDBJ
EEE58482.1
EMBL· GenBank· DDBJ
Genomic DNA
AK058750
EMBL· GenBank· DDBJ
BAG86795.1
EMBL· GenBank· DDBJ
mRNA
AK103501
EMBL· GenBank· DDBJ
BAG96116.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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