O62416 · LYS2_CAEEL
- ProteinLysozyme-like protein 2
- Genelys-2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids279 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
Involved in resistance to Gram-positive bacteria P.aeruginosa or B.thuringiensis infection.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | lysozyme activity | |
Biological Process | cell wall macromolecule catabolic process | |
Biological Process | defense response to Gram-negative bacterium | |
Biological Process | defense response to Gram-positive bacterium | |
Biological Process | innate immune response | |
Biological Process | peptidoglycan catabolic process | |
Biological Process | signal transduction |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameLysozyme-like protein 2
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionO62416
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for signal, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-19 | |||||
Sequence: MIKLLVSFTILFVLSSARP | ||||||
Chain | PRO_5004159432 | 20-279 | Lysozyme-like protein 2 | |||
Sequence: QEIDSNQAAIANTEANEAPVIVNNDASMGNAVDFSFPTNVQVMNCLKKAKYQVVFLRGFVPTGNGAFDSNCVGNIRNAYSAGLGIETYMTPQPISSWQGYQQLDLLYNGLNNNGITIRSVWIQVTSPANWPNNPTANVNFINSIISRAQQYGLSVGIYTNQYDWSQITGNSANINSNVMLWYWNVLGGGTSGETKPTFADFRAFGPFKKASVKQYAQVETVCNLVVNRDVYAVGIPAAAPKTEVNMADGEKIVVGGFVGN |
Proteomic databases
Expression
Tissue specificity
Expressed in intestine.
Induction
Induced in response to Gram-positive bacterium P.aeruginosa infection and to mitochondrial stress in the intestine (PubMed:25274306).
Induced in response to Gram-positive bacterium B.thuringiensis (B-18247) infection (PubMed:21931778).
Induced in response to Gram-positive bacterium B.thuringiensis (B-18247) infection (PubMed:21931778).
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 47-265 | Ch-type lysozyme | ||||
Sequence: MGNAVDFSFPTNVQVMNCLKKAKYQVVFLRGFVPTGNGAFDSNCVGNIRNAYSAGLGIETYMTPQPISSWQGYQQLDLLYNGLNNNGITIRSVWIQVTSPANWPNNPTANVNFINSIISRAQQYGLSVGIYTNQYDWSQITGNSANINSNVMLWYWNVLGGGTSGETKPTFADFRAFGPFKKASVKQYAQVETVCNLVVNRDVYAVGIPAAAPKTEVNM |
Sequence similarities
Belongs to the glycosyl hydrolase 25 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length279
- Mass (Da)30,291
- Last updated1998-08-01 v1
- Checksum1A451F6351F08E4E
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BX284605 EMBL· GenBank· DDBJ | CAA16324.1 EMBL· GenBank· DDBJ | Genomic DNA |