O59922 · KAPR_EMENI
- ProteincAMP-dependent protein kinase regulatory subunit
- GenepkaR
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids412 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 160-291 | 3',5'-cyclic AMP 1 (UniProtKB | ChEBI) | |||
Binding site | 238 | 3',5'-cyclic AMP 1 (UniProtKB | ChEBI) | |||
Binding site | 247 | 3',5'-cyclic AMP 1 (UniProtKB | ChEBI) | |||
Binding site | 292-405 | 3',5'-cyclic AMP 2 (UniProtKB | ChEBI) | |||
Binding site | 359 | 3',5'-cyclic AMP 2 (UniProtKB | ChEBI) | |||
Binding site | 368 | 3',5'-cyclic AMP 2 (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cAMP-dependent protein kinase complex | |
Cellular Component | cytosol | |
Cellular Component | nucleus | |
Molecular Function | cAMP binding | |
Molecular Function | cAMP-dependent protein kinase inhibitor activity | |
Molecular Function | protein kinase A catalytic subunit binding | |
Biological Process | regulation of protein phosphorylation |
Keywords
- Ligand
Names & Taxonomy
Protein names
- Recommended namecAMP-dependent protein kinase regulatory subunit
- Short namesPKA regulatory subunit
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Nidulantes
Accessions
- Primary accessionO59922
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000205408 | 1-412 | cAMP-dependent protein kinase regulatory subunit | ||
Modified residue | 120 | Phosphoserine | |||
Keywords
- PTM
Interaction
Subunit
Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer (By similarity).
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for compositional bias, region.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-17 | Polar residues | |||
Region | 1-146 | Disordered | |||
Compositional bias | 19-34 | Basic and acidic residues | |||
Region | 23-159 | Dimerization and phosphorylation | |||
Compositional bias | 40-59 | Polar residues | |||
Compositional bias | 115-142 | Polar residues | |||
Sequence similarities
Belongs to the cAMP-dependent kinase regulatory chain family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length412
- Mass (Da)44,904
- Last updated1998-08-01 v1
- Checksum40F574887A1D5CBB
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 1-17 | Polar residues | |||
Compositional bias | 19-34 | Basic and acidic residues | |||
Compositional bias | 40-59 | Polar residues | |||
Compositional bias | 115-142 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF043231 EMBL· GenBank· DDBJ | AAC18061.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AACD01000084 EMBL· GenBank· DDBJ | EAA61065.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BN001303 EMBL· GenBank· DDBJ | CBF76336.1 EMBL· GenBank· DDBJ | Genomic DNA |