O59922 · KAPR_EMENI

Function

Features

Showing features for binding site.

141250100150200250300350400
TypeIDPosition(s)Description
Binding site160-2913',5'-cyclic AMP 1 (UniProtKB | ChEBI)
Binding site2383',5'-cyclic AMP 1 (UniProtKB | ChEBI)
Binding site2473',5'-cyclic AMP 1 (UniProtKB | ChEBI)
Binding site292-4053',5'-cyclic AMP 2 (UniProtKB | ChEBI)
Binding site3593',5'-cyclic AMP 2 (UniProtKB | ChEBI)
Binding site3683',5'-cyclic AMP 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentcAMP-dependent protein kinase complex
Cellular Componentcytosol
Cellular Componentnucleus
Molecular FunctioncAMP binding
Molecular FunctioncAMP-dependent protein kinase inhibitor activity
Molecular Functionprotein kinase A catalytic subunit binding
Biological Processregulation of protein phosphorylation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    cAMP-dependent protein kinase regulatory subunit
  • Short names
    PKA regulatory subunit

Gene names

    • Name
      pkaR
    • ORF names
      AN4987

Organism names

Accessions

  • Primary accession
    O59922
  • Secondary accessions
    • C8V8P0
    • Q5B393

Proteomes

Organism-specific databases

PTM/Processing

Features

Showing features for chain, modified residue.

Type
IDPosition(s)Description
ChainPRO_00002054081-412cAMP-dependent protein kinase regulatory subunit
Modified residue120Phosphoserine

Keywords

Interaction

Subunit

Tetramer, composed of 2 regulatory (R) and 2 catalytic (C) subunits. In the presence of cAMP it dissociates into 2 active monomeric C subunits and an R dimer (By similarity).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias1-17Polar residues
Region1-146Disordered
Compositional bias19-34Basic and acidic residues
Region23-159Dimerization and phosphorylation
Compositional bias40-59Polar residues
Compositional bias115-142Polar residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    412
  • Mass (Da)
    44,904
  • Last updated
    1998-08-01 v1
  • Checksum
    40F574887A1D5CBB
MSNYSHSSNNPFLKVSTKEDKPSSFHKIAEDEEYEVTSPTDATFRASKNADNSAGGNNPLESGRAGESGDGIRFGRDPFGNFQGGAEGQDESSIDPNGFRPTGGPDHGFPNNYALGRRTSVSAESLNPTSAGSDSWTPPSHPKSEEQLARLKTAVSNNFLFSHLDDEQSRTVLDALVEKPIPAKDIKVISQGDAGDYFYIVEEGHFDVYINPSGSVQPGPDGAGTKISTIGPGGSFGELALMYNAPRAATIVSTEPKSTLWALDRITFRRILMDSAFQRRRMYEAFLEEVPLLSSLKPYERAKIADALDTIKFPAGEYIIKEGDPGDAFYLLESGEAEAFMEGVEEPVKSYKRGDYFGELALLDDKPRAASVRAKTEVKVAKLGRDGFKRLLGPVENIMRRTEYSSRPSTAT

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-17Polar residues
Compositional bias19-34Basic and acidic residues
Compositional bias40-59Polar residues
Compositional bias115-142Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF043231
EMBL· GenBank· DDBJ
AAC18061.1
EMBL· GenBank· DDBJ
Genomic DNA
AACD01000084
EMBL· GenBank· DDBJ
EAA61065.1
EMBL· GenBank· DDBJ
Genomic DNA
BN001303
EMBL· GenBank· DDBJ
CBF76336.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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