O58885 · PEPQ_PYRHO

Function

function

Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position.

Catalytic activity

Cofactor

Co2+ (UniProtKB | Rhea| CHEBI:48828 )

Note: Binds 2 cobalt ions per subunit.

Features

Showing features for binding site.

135150100150200250300350
TypeIDPosition(s)Description
Binding site212Co2+ 2 (UniProtKB | ChEBI)
Binding site223Co2+ 1 (UniProtKB | ChEBI)
Binding site223Co2+ 2 (UniProtKB | ChEBI)
Binding site287Co2+ 1 (UniProtKB | ChEBI)
Binding site316Co2+ 1 (UniProtKB | ChEBI)
Binding site330Co2+ 1 (UniProtKB | ChEBI)
Binding site330Co2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionmetal ion binding
Molecular Functionmetallopeptidase activity
Molecular Functionproline dipeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Xaa-Pro dipeptidase
  • EC number
  • Short names
    X-Pro dipeptidase
  • Alternative names
    • Imidodipeptidase
    • Proline dipeptidase (Prolidase)

Gene names

    • Name
      pepQ
    • Ordered locus names
      PH1149

Organism names

Accessions

  • Primary accession
    O58885

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001850941-351Xaa-Pro dipeptidase

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    351
  • Mass (Da)
    39,401
  • Last updated
    1998-08-01 v1
  • Checksum
    38CB76FFFB766A7E
MDIMNEKVKKIIEFMDKNSIDAVLIAKNPNVYYISGASPLAGGYILITGESATLYVPELEYEMAKEESNIPVEKFKKMDEFYKALEGIKSLGIESSLPYGFIEELKKKANIKEFKKVDDVIRDMRIIKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIASGYRSALPHGVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGHGVGLEVHEWPRVSQYDETVLREGMVITIEPGIYIPKIGGVRIEDTILITKNGSKRLTKTERELI

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BA000001
EMBL· GenBank· DDBJ
BAA30249.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp