O57380 · ADH8_PELPE

Function

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions per subunit.

Features

Showing features for binding site.

137350100150200250300350
TypeIDPosition(s)Description
Binding site47Zn2+ 1 (UniProtKB | ChEBI); catalytic
Binding site68Zn2+ 1 (UniProtKB | ChEBI); catalytic
Binding site98Zn2+ 2 (UniProtKB | ChEBI)
Binding site101Zn2+ 2 (UniProtKB | ChEBI)
Binding site104Zn2+ 2 (UniProtKB | ChEBI)
Binding site112Zn2+ 2 (UniProtKB | ChEBI)
Binding site174Zn2+ 1 (UniProtKB | ChEBI); catalytic

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionalcohol dehydrogenase (NADP+) activity
Molecular Functionall-trans-retinol dehydrogenase (NAD+) activity
Molecular Functionzinc ion binding
Biological Processretinoic acid metabolic process
Biological Processretinol metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADP-dependent alcohol dehydrogenase
  • EC number

Gene names

    • Name
      ADH8

Organism names

Accessions

  • Primary accession
    O57380

Subcellular Location

PTM/Processing

Features

Showing features for initiator methionine, modified residue, chain.

Type
IDPosition(s)Description
Initiator methionine1Removed
Modified residue2N-acetylcysteine
ChainPRO_00001607562-373NADP-dependent alcohol dehydrogenase

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    373
  • Mass (Da)
    39,168
  • Last updated
    2007-01-23 v3
  • Checksum
    954A502267E8DE49
MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPSKFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAKTGLMADMTSRFTCRGKPIYNLVGTSTFTEYTVVADIAVAKIDPKAPLESCLIGCGFATGYGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATECLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNERLPLDPLLLLTGRSLKGSVFGGFKGEEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAFELLSSGQGVRSIMIY

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict74in Ref. 1; AA sequence
Sequence conflict134in Ref. 1; AA sequence
Sequence conflict142in Ref. 1; AA sequence

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ002554
EMBL· GenBank· DDBJ
CAA05553.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

Disclaimer

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