Cloning and characterization of an actin-resistant DNase I-like endonuclease secreted by macrophages.Baron W.F., Pan C.Q., Spencer S.A., Ryan A.M., Lazarus R.A., Baker K.P.View abstractCited forNUCLEOTIDE SEQUENCE [MRNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGene 215:291-301 (1998)Cited in2Mapped to2
Characterization of the murine DNase gamma gene.Shiokawa D., Tanuma S.Cited forNUCLEOTIDE SEQUENCEStrainC57BL/6JCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)Submission Submitted to EMBL/GenBank/DDBJ databases (JAN-2001)Cited in1
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]TissueLiverCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
A role of the Ca2+/Mg2+-dependent endonuclease in apoptosis and its inhibition by poly(ADP-ribose) polymerase.Yakovlev A.G., Wang G., Stoica B.A., Boulares H.A., Spoonde A.Y., Yoshihara K., Smulson M.E.View abstractCited forTISSUE SPECIFICITY, DEVELOPMENTAL STAGECategoriesExpressionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 275:21302-21308 (2000)Cited in2
Involvement of DNase gamma in apoptosis associated with myogenic differentiation of C2C12 cells.Shiokawa D., Kobayashi T., Tanuma S.View abstractCited forFUNCTION, SUBCELLULAR LOCATIONCategoriesFunction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 277:31031-31037 (2002)Cited in1Mapped to2
Deoxyribonuclease I-like III is an inducible macrophage barrier to liposomal transfection.Wilber A., Lu M., Schneider M.C.View abstractCited forFUNCTION, SUBCELLULAR LOCATIONCategoriesFunction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Ther. 6:35-42 (2002)Cited in1
Differential DNases are selectively used in neuronal apoptosis depending on the differentiation state.Shiokawa D., Tanuma S.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Death Differ. 11:1112-1120 (2004)Cited in2
Comparative characterization of rat deoxyribonuclease 1 (Dnase1) and murine deoxyribonuclease 1-like 3 (Dnase1l3).Napirei M., Wulf S., Eulitz D., Mannherz H.G., Kloeckl T.View abstractCited forFUNCTION, SUBCELLULAR LOCATION, COFACTOR, ACTIVITY REGULATIONCategoriesFunction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBiochem. J. 389:355-364 (2005)Cited in2Mapped to10
Stage-specific expression of DNasegamma during B-cell development and its role in B-cell receptor-mediated apoptosis in WEHI-231 cells.Shiokawa D., Shika Y., Araki S., Sunaga S., Mizuta R., Kitamura D., Tanuma S.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Death Differ. 14:992-1000 (2007)Cited in1Mapped to2
Murine serum nucleases--contrasting effects of plasmin and heparin on the activities of DNase1 and DNase1-like 3 (DNase1l3).Napirei M., Ludwig S., Mezrhab J., Kloeckl T., Mannherz H.G.View abstractCited forFUNCTION, ACTIVITY REGULATIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCFEBS J. 276:1059-1073 (2009)Cited in1Mapped to11
DNase gamma is the effector endonuclease for internucleosomal DNA fragmentation in necrosis.Mizuta R., Araki S., Furukawa M., Furukawa Y., Ebara S., Shiokawa D., Hayashi K., Tanuma S., Kitamura D.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCPLoS ONE 8:E80223-E80223 (2013)Cited in2Mapped to6
Digestion of chromatin in apoptotic cell microparticles prevents autoimmunity.Sisirak V., Sally B., D'Agati V., Martinez-Ortiz W., Oezcakar Z.B., David J., Rashidfarrokhi A., Yeste A., Panea C.[...], Reizis B.View abstractCited forFUNCTION, SUBCELLULAR LOCATION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITYCategoriesFunction, Expression, Phenotypes & Variants, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 166:88-101 (2016)Cited in2Mapped to21
Host DNases prevent vascular occlusion by neutrophil extracellular traps.Jimenez-Alcazar M., Rangaswamy C., Panda R., Bitterling J., Simsek Y.J., Long A.T., Bilyy R., Krenn V., Renne C.[...], Fuchs T.A.View abstractCited forFUNCTION, DISRUPTION PHENOTYPECategoriesFunction, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 358:1202-1206 (2017)Cited in2Mapped to10
Dnase1l3 deficiency in lupus-prone MRL and NZB/W F1 mice.Wilber A., O'Connor T.P., Lu M.L., Karimi A., Schneider M.C.View abstractCited forVARIANT ILE-89, CHARACTERIZATION OF ILE-89, POSSIBLE INVOLVEMENT IN SLECategoriesSequences, Phenotypes & VariantsSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCClin. Exp. Immunol. 134:46-52 (2003)Cited in1Mapped to13
Double-negative B cells and DNASE1L3 colocalise with microbiota in gut- associated lymphoid tissue.Montorsi L., Pitcher M.J., Zhao Y., Dionisi C., Demonti A., Tull T.J., Dhami P., Ellis R.J., Bishop C.[...], Spencer J.View abstractAnnotationDouble-negative B cells and DNASE1L3 colocalise with microbiota in gut-associated lymphoid tissue.SourceGeneRif: 13421PubMedEurope PMCNat Commun 15:4051-4051 (2024)Mapped to6
The deficiency of DNASE1L3 does not affect systemic sclerosis pathogenesis in two inducible murine models of the disease.Garreau A., Santa P., Dubois M., Brisou D., Levionnois E., Laurent P., Ferriere A., Roubertie A., Loizon S.[...], Sisirak V.View abstractAnnotationThe deficiency of DNASE1L3 does not affect systemic sclerosis pathogenesis in two inducible murine models of the disease.SourceGeneRif: 13421PubMedEurope PMCEur J Immunol 54:e2350903-e2350903 (2024)Mapped to3
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractSourceMGI: 1314633PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Neutrophil extracellular traps and DNases orchestrate formation of peritoneal adhesions.Elrod J., Heuer A., Knopf J., Schoen J., Schonfeld L., Trochimiuk M., Stiel C., Appl B., Raluy L.P.[...], Boettcher M.View abstractSourceMGI: 1314633PubMedEurope PMCiScience 26:108289-108289 (2023)Mapped to12
Deficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice.Engavale M., Hernandez C.J., Infante A., LeRoith T., Radovan E., Evans L., Villarreal J., Reilly C.M., Sutton R.B., Keyel P.A.View abstractAnnotationDeficiency of macrophage-derived Dnase1L3 causes lupus-like phenotypes in mice.CategoriesFunctionSourceGeneRif: 13421, MGI: 1314633PubMedEurope PMCJ Leukoc Biol 114:547-556 (2023)Mapped to5
DNASE1L3 enhances antitumor immunity and suppresses tumor progression in colon cancer.Li W., Nakano H., Fan W., Li Y., Sil P., Nakano K., Zhao F., Karmaus P.W., Grimm S.A.[...], Li L.View abstractAnnotationDNASE1L3 enhances antitumor immunity and suppresses tumor progression in colon cancer.CategoriesFunctionSourceGeneRif: 13421, MGI: 1314633PubMedEurope PMCJCI Insight 8:e168161-e168161 (2023)Mapped to3
Targeting NETs using dual-active DNase1 variants.Englert H., Gobel J., Khong D., Omidi M., Wolska N., Konrath S., Frye M., Mailer R.K., Beerens M.[...], Renne T.View abstractSourceMGI: 1314633PubMedEurope PMCFront Immunol 14:1181761-1181761 (2023)Mapped to12
Epistatic effects of Siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus.Korn M.A., Steffensen M., Brandl C., Royzman D., Daniel C., Winkler T.H., Nitschke L.View abstractAnnotationEpistatic effects of Siglec-G and DNase1 or DNase1l3 deficiencies in the development of systemic lupus erythematosus.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 13421, MGI: 1314633PubMedEurope PMCFront Immunol 14:1095830-1095830 (2023)Mapped to15
Secreted mammalian DNases protect against systemic bacterial infection by digesting biofilms.Lacey K.A., Serpas L., Makita S., Wang Y., Rashidfarrokhi A., Soni C., Gonzalez S., Moreira A., Torres V.J., Reizis B.View abstractCategoriesFunctionSourceMGI: 1314633PubMedEurope PMCJ Exp Med 220:e20221086-e20221086 (2023)Mapped to11
B cell-intrinsic DNase1L3 is essential for the T cell-independent type II response in mice.Kato K., Haniuda K., Fukao S., Kitamura D.View abstractAnnotationB cell-intrinsic DNase1L3 is essential for the T cell-independent type II response in mice.CategoriesFunction, Subcellular LocationSourceGeneRif: 13421PubMedEurope PMCInt Immunol 35:275-286 (2023)Mapped to3
Effects of nucleases on cell-free extrachromosomal circular DNA.Sin S.T., Deng J., Ji L., Yukawa M., Chan R.W., Volpi S., Vaglio A., Fenaroli P., Bocca P.[...], Lo Y.M.D.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1314633PubMedEurope PMCJCI Insight 7:e156070-e156070 (2022)Mapped to11