O54758 · ALMS_TAMSI

Function

function

Serine protease inhibitor.

Features

Showing features for site.

141350100150200250300350400
TypeIDPosition(s)Description
Site377-378Reactive bond

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentextracellular space
Molecular Functionserine-type endopeptidase inhibitor activity

Keywords

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Alpha-1-antitrypsin-like protein CM55-MS

Organism names

Accessions

  • Primary accession
    O54758

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, modified residue, chain, glycosylation.

TypeIDPosition(s)Description
Signal1-24
Modified residue25Pyrrolidone carboxylic acid
ChainPRO_000003240425-413Alpha-1-antitrypsin-like protein CM55-MS
Glycosylation65N-linked (GlcNAc...) asparagine
Glycosylation102N-linked (GlcNAc...) asparagine
Glycosylation165N-linked (GlcNAc...) asparagine
Glycosylation266N-linked (GlcNAc...) asparagine

Keywords

Expression

Tissue specificity

Expressed in liver.

Structure

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region368-387RCL

Domain

The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the serpin reactive site and the active site of the protease. The resulting inactive serpin-protease complex is highly stable (By similarity).

Sequence similarities

Belongs to the serpin family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    413
  • Mass (Da)
    45,952
  • Last updated
    1998-06-01 v1
  • Checksum
    430374CA26EBAF08
MPSSISWGLLLLAALSCLGPGSLAQDAQETEASKQDQEHPASHRIAPHLAEFALSLYRVLARQSNTTNIFFSPVSIATALAMLSLGTKGDTHTQILEGLDFNLTEMAEADIHQGFQHLLQTLNRPNTQLQLTSGNGLFIHQNLKLLDKFLEDVKSLYHSEAFPTNFTNMEEARQQINSYVEKGTQGKIVELVKELDSDTVLALVNYIFFKGKWLKPFNEEHTREEDFHVDEATTVRVPMMNREGRFHLHHCSTLASWVLQMDYLGNATAIFLLPDEGKMQHLEDTVSTEILSKFLKNRQTTRVSLYFPKVSISGTYALKTVLSSLGITKVFSNAADLSGVTEEAPLIVSKALHKAVLDIDEEGTEAAGATVGGITFMSRPKEVIFDRPFLVVIYEHHTKSPLFVGKVVNPTQQ

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB000547
EMBL· GenBank· DDBJ
BAA24417.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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