O48950 · TATB_MAIZE

  • Protein
    Sec-independent protein translocase protein TATB, chloroplastic
  • Gene
    TATB
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    4/5

Function

function

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across the thylakoid membrane. Involved in delta pH-dependent protein transport required for chloroplast development, especially thylakoid membrane formation. TATC and TATB mediate precursor recognition, whereas TATA facilitates translocation.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast thylakoid membrane
Molecular Functionproton motive force dependent protein transmembrane transporter activity
Biological Processprotein import into chloroplast thylakoid membrane
Biological Processprotein transport by the Tat complex

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Sec-independent protein translocase protein TATB, chloroplastic
  • Alternative names
    • Protein HIGH CHLOROPHYLL FLUORESCENCE 106
    • Protein TWIN-ARGININE TRANSLOCATION B

Gene names

    • Name
      TATB
    • Synonyms
      HCF106
    • ORF names
      ZEAMMB73_Zm00001d003913

Organism names

  • Taxonomic identifier
  • Strain
    • cv. B73
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea

Accessions

  • Primary accession
    O48950
  • Secondary accessions
    • A0A1D6ECA8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Plastid, chloroplast thylakoid membrane
; Single-pass membrane protein
Note: The C-terminus is located in the stroma.

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain68-69Lumenal
Transmembrane70-90Helical
Topological domain91-243Stromal

Keywords

Phenotypes & Variants

Disruption phenotype

Seedling lethality. Non-photosynthetic mutants possess near normal pigment levels but lack one or more elements of the electron transport activity in chloroplasts. Defects in protein targeting across chloroplast thylakoid membrane (PubMed:7664731).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 11 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for transit peptide, chain.

TypeIDPosition(s)Description
Transit peptide1-67Chloroplast
ChainPRO_000041991668-243Sec-independent protein translocase protein TATB, chloroplastic

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

In thylakoid membranes, TATC and TATB form a large receptor complex, containing about eight TATC-TATB pairs, which binds the precursor protein. Twin arginine signal peptide promotes pH-triggered docking of TATA oligomers to TATC-TATB receptor complex, inducing a conformational switch of TATA that results in activation of the translocase. TATA dissociates from TATC-TATB upon completion of translocation (By similarity).

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region129-165Disordered
Compositional bias131-155Polar residues
Region178-243Disordered
Compositional bias183-210Polar residues

Sequence similarities

Belongs to the TatB family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    243
  • Mass (Da)
    26,326
  • Last updated
    1998-06-01 v1
  • Checksum
    98A1EE715BABA385
MTPTANLLLPAPPFVPISDVRRLQLPPRVRHQPRPCWKGVEWGSIQTRMVSSFVAVGSRTRRRNVICASLFGVGAPEALVIGVVALLVFGPKGLAEVARNLGKTLRAFQPTIRELQDVSREFRSTLEREIGIDEVSQSTNYRPTTMNNNQQPAADPNVKPEPAPYTSEELMKVTEEQIAASAAAAWNPQQPATSQQQEEAPTTPRSEDAPTSGGSDGPAAPARAVSDSDPNQVNKSQKAEGER

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A804MH45A0A804MH45_MAIZE732790241

Sequence caution

The sequence ONM17954.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias131-155Polar residues
Compositional bias183-210Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF027808
EMBL· GenBank· DDBJ
AAC01571.1
EMBL· GenBank· DDBJ
mRNA
CM007648
EMBL· GenBank· DDBJ
ONM17954.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
BT068439
EMBL· GenBank· DDBJ
ACN35336.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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