O48929 · ETR1_TOBAC
- ProteinEthylene receptor
- GeneETR1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids738 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
function
May act early in the ethylene signal transduction pathway, possibly as an ethylene receptor, or as a regulator of the pathway.
Catalytic activity
Cofactor
Note: Binds 1 copper ion per dimer.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 64 | Cu cation (UniProtKB | ChEBI) | |||
Binding site | 68 | Cu cation (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | endoplasmic reticulum membrane | |
Molecular Function | ATP binding | |
Molecular Function | ethylene binding | |
Molecular Function | ethylene receptor activity | |
Molecular Function | metal ion binding | |
Molecular Function | phosphorelay sensor kinase activity | |
Biological Process | negative regulation of ethylene-activated signaling pathway |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameEthylene receptor
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > asterids > lamiids > Solanales > Solanaceae > Nicotianoideae > Nicotianeae > Nicotiana
Accessions
- Primary accessionO48929
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Endoplasmic reticulum membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 22-42 | Helical | |||
Transmembrane | 53-73 | Helical | |||
Transmembrane | 91-111 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain, disulfide bond, modified residue.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000081423 | 1-738 | Ethylene receptor | ||
Disulfide bond | 3 | Interchain | |||
Disulfide bond | 5 | Interchain | |||
Modified residue | 351 | Phosphohistidine; by autocatalysis | |||
Modified residue | 661 | 4-aspartylphosphate | |||
Post-translational modification
Activation probably requires a transfer of a phosphate group between a His in the transmitter domain and an Asp of the receiver domain.
Keywords
- PTM
Proteomic databases
Expression
Induction
Constitutive expression. Not induced by senescence, wounding, application of ethephon or infection with virus.
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 157-305 | GAF | |||
Domain | 348-585 | Histidine kinase | |||
Domain | 613-730 | Response regulatory | |||
Sequence similarities
Belongs to the ethylene receptor family.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length738
- Mass (Da)82,294
- Last updated1998-06-01 v1
- ChecksumD6C5F7B16F16A7DE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF022727 EMBL· GenBank· DDBJ | AAB97160.1 EMBL· GenBank· DDBJ | mRNA |