O44441 · ATIF2_CAEEL

  • Protein
    ATPase inhibitor mai-2, mitochondrial
  • Gene
    mai-2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Thought to be a regulatory component of the ATP-synthesizing complex in the mitochondria. Activity is pH dependent.

Miscellaneous

Mai-2 and tin-9.2 are transcribed on a dicistronic transcript where exos-4.1 is the upstream transcript and tin-9.2 the downstream.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmitochondrion
Molecular FunctionATPase binding
Molecular FunctionATPase inhibitor activity
Biological Processheme biosynthetic process
Biological Processnegative regulation of ATP-dependent activity
Biological Processnegative regulation of nucleotide metabolic process

Names & Taxonomy

Protein names

  • Recommended name
    ATPase inhibitor mai-2, mitochondrial
  • Alternative names
    • ATP synthase F1 subunit epsilon

Gene names

    • Name
      mai-2
    • ORF names
      B0546.1

Organism names

  • Taxonomic identifier
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    O44441

Proteomes

Organism-specific databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, transit peptide.

Type
IDPosition(s)Description
ChainPRO_0000002552?-109ATPase inhibitor mai-2, mitochondrial
Transit peptide1-?Mitochondrion

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, coiled coil.

Type
IDPosition(s)Description
Region18-39Disordered
Coiled coil55-109
Region73-109Disordered

Sequence similarities

Belongs to the ATPase inhibitor family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    109
  • Mass (Da)
    12,031
  • Last updated
    1998-06-01 v1
  • Checksum
    AE79F12221D2FF79
MLSVSRAATRMTGMVARFSAGGHGDGAGRGGGSGGSIRDAGGAFGKMEAAREDEYFYKKQKAQLQELREHIQEEVKHHEGQLENHKKVLERHQQRISEIEAQERALGKE

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FO080229
EMBL· GenBank· DDBJ
CCD62188.1
EMBL· GenBank· DDBJ
Genomic DNA
AF326939
EMBL· GenBank· DDBJ
AAG49389.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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