The 5-prime region of the COX4 gene contains a novel overlapping gene, NOC4.Bachman N.J., Wu W., Schmidt T.R., Grossman L.I., Lomax M.I.View abstractCited forNUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 1)TissuePlacenta, RetinaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMamm. Genome 10:506-512 (1999)Cited in3Mapped to11
The sequence and analysis of duplication-rich human chromosome 16.Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M.[...], Pennacchio L.A.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 432:988-994 (2004)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)TissueEpidermal carcinoma, Muscle, PlacentaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Initial characterization of the human central proteome.Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCBMC Syst. Biol. 5:17-17 (2011)Cited in99+99+
Defining human ERAD networks through an integrative mapping strategy.Christianson J.C., Olzmann J.A., Shaler T.A., Sowa M.E., Bennett E.J., Richter C.M., Tyler R.E., Greenblatt E.J., Harper J.W., Kopito R.R.View abstractCited forIDENTIFICATION IN THE EMC COMPLEX, SUBCELLULAR LOCATIONCategoriesInteraction, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Cell Biol. 14:93-105 (2012)Cited in10
N-terminome analysis of the human mitochondrial proteome.Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M., Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCProteomics 15:2519-2524 (2015)Cited in99+99+
EMC Is Required to Initiate Accurate Membrane Protein Topogenesis.Chitwood P.J., Juszkiewicz S., Guna A., Shao S., Hegde R.S.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell 175:1507-1519 (2018)Cited in10
The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins.Shurtleff M.J., Itzhak D.N., Hussmann J.A., Schirle Oakdale N.T., Costa E.A., Jonikas M., Weibezahn J., Popova K.D., Jan C.H.[...], Weissman J.S.View abstractCited forFUNCTIONCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 7:0-0 (2018)Cited in17
The ER membrane protein complex is a transmembrane domain insertase.Guna A., Volkmar N., Christianson J.C., Hegde R.S.View abstractCited forFUNCTION, SUBUNITCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 359:470-473 (2018)Cited in10Mapped to44
The architecture of EMC reveals a path for membrane protein insertion.O'Donnell J.P., Phillips B.P., Yagita Y., Juszkiewicz S., Wagner A., Malinverni D., Keenan R.J., Miller E.A., Hegde R.S.View abstractCited forFUNCTION, SUBUNITCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCElife 9:0-0 (2020)Cited in10
Structural basis for membrane insertion by the human ER membrane protein complex.Pleiner T., Tomaleri G.P., Januszyk K., Inglis A.J., Hazu M., Voorhees R.M.View abstractCited forSTRUCTURE BY ELECTRON MICROSCOPY (3.40 ANGSTROMS) OF THE EMC COMPLEX, FUNCTION, TOPOLOGYCategoriesFunction, Interaction, Structure, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCScience 369:433-436 (2020)Cited in9
Structural insights into human EMC and its interaction with VDAC.Li M., Zhang C., Xu Y., Li S., Huang C., Wu J., Lei M.View abstractCategoriesStructureSourcePDB: 8J0N, PDB: 8J0OPubMedEurope PMCAging (Albany NY) 16:5501-5525 (2024)Mapped to10
A selectivity filter in the ER membrane protein complex limits protein misinsertion at the ER.Pleiner T., Hazu M., Pinton Tomaleri G., Nguyen V.N., Januszyk K., Voorhees R.M.View abstractCategoriesStructureSourcePDB: 8S9SPubMedEurope PMCJ Cell Biol 222:e202212007-e202212007 (2023)Mapped to9
EMC chaperone-Capisub>Vpi/sub> structure reveals an ion channel assembly intermediate.Chen Z., Mondal A., Abderemane-Ali F., Jang S., Niranjan S., Montano J.L., Zaro B.W., Minor D.L. Jr.View abstractCategoriesStructureSourcePDB: 8EOIPubMedEurope PMCNature 619:410-419 (2023)Mapped to39
Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients.Miller-Vedam L.E., Brauning B., Popova K.D., Schirle Oakdale N.T., Bonnar J.L., Prabu J.R., Boydston E.A., Sevillano N., Shurtleff M.J.[...], Weissman J.S.View abstractCategoriesStructureSourcePDB: 7ADO, PDB: 7ADPPubMedEurope PMCElife 9:e62611-e62611 (2020)Mapped to17
A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface.Gupta G.D., Coyaud E., Goncalves J., Mojarad B.A., Liu Y., Wu Q., Gheiratmand L., Comartin D., Tkach J.M.[...], Pelletier L.View abstractCategoriesInteractionSourceIntAct: O43402PubMedEurope PMCCell 163:1484-1499 (2015)Cited in9Mapped to99+
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.Hein M.Y., Hubner N.C., Poser I., Cox J., Nagaraj N., Toyoda Y., Gak I.A., Weisswange I., Mansfeld J.[...], Mann M.View abstractCategoriesInteractionSourceIntAct: O43402PubMedEurope PMCCell 163:712-723 (2015)Mapped to99+
TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex.Guarani V., Paulo J., Zhai B., Huttlin E.L., Gygi S.P., Harper J.W.View abstractCategoriesInteractionSourceIntAct: O43402PubMedEurope PMCMol Cell Biol 34:847-861 (2014)Mapped to99+
MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.Zhang X., Yang H., Lee J.J., Kim E., Lippman S.M., Khuri F.R., Spitz M.R., Lotan R., Hong W.K., Wu X.View abstractAnnotationObservational study of gene-disease association and gene-gene interaction. (HuGE Navigator)CategoriesSequences, Disease & VariantsSourceGeneRif: 10328PubMedEurope PMCCarcinogenesis 31:2118-2123 (2010)Mapped to99+
Association of genetic variants with hemorrhagic stroke in Japanese individuals.Yoshida T., Kato K., Yokoi K., Oguri M., Watanabe S., Metoki N., Yoshida H., Satoh K., Aoyagi Y.[...], Yamada Y.View abstractAnnotationObservational study of gene-disease association. (HuGE Navigator)CategoriesSequences, Disease & VariantsSourceGeneRif: 10328PubMedEurope PMCInt J Mol Med 25:649-656 (2010)Mapped to99+
Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.Oguri M., Kato K., Yokoi K., Yoshida T., Watanabe S., Metoki N., Yoshida H., Satoh K., Aoyagi Y.[...], Yamada Y.View abstractAnnotationNot Associated with CARDIOVASCULAR: hypertension., Observational study of gene-disease association. (HuGE Navigator)CategoriesDisease & Variants, Function, Sequences, Disease & VariantsSourceGAD:592851, GeneRif: 10328PubMedEurope PMCAm J Hypertens 23:70-77 (2010)Mapped to99+
Association of gene polymorphisms with chronic kidney disease in Japanese individuals.Yoshida T., Kato K., Yokoi K., Oguri M., Watanabe S., Metoki N., Yoshida H., Satoh K., Aoyagi Y.[...], Yamada Y.View abstractAnnotationObservational study of gene-disease association. (HuGE Navigator)CategoriesSequencesSourceGeneRif: 10328PubMedEurope PMCInt J Mol Med 24:539-547 (2009)Mapped to99+
Large-scale mapping of human protein-protein interactions by mass spectrometry.Ewing R.M., Chu P., Elisma F., Li H., Taylor P., Climie S., McBroom-Cerajewski L., Robinson M.D., O'Connor L.[...], Figeys D.View abstractCategoriesInteractionSourceIntAct: O43402PubMedEurope PMCMol Syst Biol 3:89-89 (2007)Mapped to99+
Towards a proteome-scale map of the human protein-protein interaction network.Rual J.F., Venkatesan K., Hao T., Hirozane-Kishikawa T., Dricot A., Li N., Berriz G.F., Gibbons F.D., Dreze M.[...], Vidal M.View abstractCategoriesInteractionSourceIntAct: O43402PubMedEurope PMCNature 437:1173-1178 (2005)Cited in1Mapped to99+