O42500 · O42500_MELGA

Function

function

Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentplasma membrane
Molecular FunctionG protein-coupled peptide receptor activity
Molecular Functionluteinizing hormone receptor activity
Biological Processactivation of adenylate cyclase activity
Biological Processadenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological Processhormone-mediated signaling pathway
Biological Processmale gonad development
Biological Processovarian follicle development
Biological Processovulation cycle process
Biological Processphospholipase C-activating G protein-coupled receptor signaling pathway

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Lutropin-choriogonadotropic hormone receptor

Gene names

    • Name
      LHCGR

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Meleagridinae > Meleagris

Accessions

  • Primary accession
    O42500

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane262-283Helical
Transmembrane295-316Helical
Transmembrane340-360Helical
Transmembrane381-404Helical
Transmembrane424-449Helical
Transmembrane470-492Helical
Transmembrane504-524Helical

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain274-521G-protein coupled receptors family 1 profile

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.

Keywords

Family and domain databases

Protein family/group databases

Sequence

  • Sequence status
    Fragment
  • Length
    601
  • Mass (Da)
    67,381
  • Last updated
    1998-01-01 v1
  • Checksum
    714D2FD6D5E28FDC
LILNTKNLLHIEDGAFRNLPRLKYLSICNTGIIEFPDLTQIFSSEAHFILELCDNLHMTTIPQNAFQGMSNESLTLKLYKNGFEDIHSHAFNGTKLNQLILKDNKNLRRIHNDALRGATGPDVLDISSTALESLPSYGLEAIQVLNAESSYSLKRLPPLDKFSSLLEAVLTYPSHCCAFRNLRTEKQNSMLSIFDNFSKRCESIVRKTTSEIFYRDASFNTSLGQRKSTRTHLEQPKILTCTPEPDAFNPCEDILGYSFLRVLIWFINILAIAGNLIVLLVLITSHYKLMVPRFLMCNLSFADFCMGLYLVLIASVDAQTSGQYYNHAIYWQTGSGCSTAGFFTVFASELSVYTLTVITIERWHTITYAMQLDRQLRLRHAVLIMLGGWVFSILIAVLPLLGVSSYMKVSICLPMDIETGLSQAYILLILVLNAVAFVVICACYIKIYIAVQNPELVAANKDTKIAKRMAILIFTDFTCMAPISFFAISAAFKVPLITVTNSKILLVLFYPVNSCANPFLYAIFTKAFQRDFFLLMSKLGCCKSRAELCRMNYFSAYTSNCKNGSSAPGPSKASQALLLLSASEKLCKTRRSTKKSQPECQ

Features

Showing features for non-terminal residue.

TypeIDPosition(s)Description
Non-terminal residue1

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U92082
EMBL· GenBank· DDBJ
AAB64409.1
EMBL· GenBank· DDBJ
mRNA

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